126924-38-7
126924-38-7
Chemical Structure
(S)-Norfluoxetine
- CAS No.: 126924-38-7
- Formula:C16H16F3NO
- Molecular Weight:295.30
IUPAC Name: (S)-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine
InChIKey: WIQRCHMSJFFONW-HNNXBMFYSA-N
SMILES: FC(F)(F)C1=CC=C(O[C@@H](CCN)C2=CC=CC=C2)C=C1
Biological Activity: (S)-Norfluoxetine, a S enantiomer of Norfluoxetine (HY-135556), is a selective serotonin reuptake inhibitor. (S)-Norfluoxetine can increase allopregnanolone levels and reduce aggression in socially isolated mice[1][2].
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(S)-Norfluoxetine | (S)-Norfluoxetine, a S enantiomer of Norfluoxetine (HY-135556), is a selective serotonin reuptake inhibitor. (S)-Norfluoxetine can increase allopregnanolone levels and reduce aggression in socially isolated mice. | |||||||||||||||||||||
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(R)-Norfluoxetine-d5 | (R)-Norfluoxetine-d5 is the deuterium labeled (R)-Norfluoxetine. | |||||||||||||||||||||
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(S)-Norfluoxetine-d5 | (S)-Norfluoxetine (phenyl) is the deuterium labeled (S)-Norfluoxetine-d5 (phenyl-. | |||||||||||||||||||||
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References
- [1]. Wong DT, et, al. Norfluoxetine enantiomers as inhibitors of serotonin uptake in rat brain. Neuropsychopharmacology. 1993 Jun;8(4):337-44. [Content Brief]
- [2]. Nelson M, et, al. S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice. Neuropharmacology. 2011 Jun;60(7-8):1154-9. [Content Brief]
