STING-IN-11
Based on 1 Customer Validation
STING-IN-11 (Compound 42) is an orally active STING inhibitor with an IC50 of 37.8 nM. STING-IN-11 can block the palmitoylation of the STING protein and STING downstream signaling, and inhibit STING-mediated inflammation. STING-IN-11 has good in vivo safety and can be used for the research of STING-related inflammatory and autoimmune diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.65%
- CAS 番号: 2925028-15-3
- 分子式: C21H20ClF2N3O
- 分子量:403.85
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
化学情報
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CAS 番号 2925028-15-3
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性状 Solid
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分子量 403.85
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分子式 C21H20ClF2N3O
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Color White to off-white
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SMILES
O=C(NC1=CNC2=C1C=C(Cl)C=C2)NC3=CC=C(C4CCC(F)(CC4)F)C=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (247.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4762 mL | 12.3808 mL | 24.7617 mL | 61.9042 mL |
| 5 mM | 0.4952 mL | 2.4762 mL | 4.9523 mL | 12.3808 mL | |
| 10 mM | 0.2476 mL | 1.2381 mL | 2.4762 mL | 6.1904 mL | |
| 15 mM | 0.1651 mL | 0.8254 mL | 1.6508 mL | 4.1269 mL | |
| 20 mM | 0.1238 mL | 0.6190 mL | 1.2381 mL | 3.0952 mL | |
| 25 mM | 0.0990 mL | 0.4952 mL | 0.9905 mL | 2.4762 mL | |
| 30 mM | 0.0825 mL | 0.4127 mL | 0.8254 mL | 2.0635 mL | |
| 40 mM | 0.0619 mL | 0.3095 mL | 0.6190 mL | 1.5476 mL | |
| 50 mM | 0.0495 mL | 0.2476 mL | 0.4952 mL | 1.2381 mL | |
| 60 mM | 0.0413 mL | 0.2063 mL | 0.4127 mL | 1.0317 mL | |
| 80 mM | 0.0310 mL | 0.1548 mL | 0.3095 mL | 0.7738 mL | |
| 100 mM | 0.0248 mL | 0.1238 mL | 0.2476 mL | 0.6190 mL |
STING-IN-11 関連分類
HY-170949 関連分類
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