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TLR8 agonist 9

TLR8 agonist 9 (Compound II-77) is an agonist for Toll-like receptor 8 (TLR8) with EC50 of 0.25-1 μM. TLR8 agonist 9 is stable in human and murine plasma, induces secretion of cytokines TNFα, with EC50 <1 μM. TLR8 agonist 9 exhibits antitumor activity in MC38-HER2 xenograft mouse model with a tumor growth inhibition (TGI) rate of 97%.

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  • CAS 番号: 3034750-61-0
  • 分子式: C38H43N7O8
  • 分子量:725.79
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • TLR8 agonist 9 Chemical Structure
    TLR8 agonist 9 構造式
CAS 番号: 3034750-61-0
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