Cavrotolimod
Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.
For research use only. We do not sell to patients.
- CAS No.: 2378664-12-9
- Formula: C300H423N71O161P26S23
- Molecular Weight:9142.88
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
CAS No. 2378664-12-9
-
Molecular Weight 9142.88
-
Formula C300H423N71O161P26S23
-
SMILES
[Cavrotolimod]
-
Synonyms
AST-008
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Daniel WL, Lorch U, Mix S, Bexon AS. A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation. Front Immunol. 2022;13:1073777. [Content Brief]
[2]. Rubatto M, Sciamarrelli N, Borriello S, et al. Classic and new strategies for the treatment of advanced melanoma and non-melanoma skin cancer. Front Med (Lausanne). 2023;9:959289. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)