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Cat. No.: HY-N19646

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[8]-Dehydrogingerdione

[8]-Dehydrogingerdione is a Hydroxyphenylalkanone. [8]-Dehydrogingerdione can be isolated from the seeds of Aframomum melegueta and the rhizomes of Curcuma xanthorrhia. [8]-Dehydrogingerdione acts as an inhibitor of α-glucosidase and Tyrosinase, with an IC₅₀ value of 19.5 μM against α-glucosidase and an approximate IC₅₀ value of 100 μM against tyrosinase. [8]-Dehydrogingerdione can be used in diabetes-related research.

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CAS No.: 77334-08-8
화학식: C₁₉H₂₆O₄
분자량:318.41

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

[8]-Dehydrogingerdione Chemical Structure

CAS No.: 77334-08-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

IC₅₀ & Target^[1]

α‑glucosidase

19.5 μM (IC₅₀)

Tyrosinase

100 μM (IC₅₀)

In Vitro

[8]-Dehydrogingerdione (1.0-100 μM; 30 min) moderately inhibits mushroom tyrosinase, with an IC₅₀ value of approximately 100 μM^[1].
[8]-Dehydrogingerdione (1-100 μM; 30 min) potently inhibits α-glucosidase from Saccharomyces cerevisiae, with an IC₅₀ value of 19.5 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 77334-08-8
분자량 318.41
화학식 C₁₉H₂₆O₄
SMILES

CCCCCCCC(CC(/C=C/C1=CC(OC)=C(C=C1)O)=O)=O
Structure Classification
- Phenols
- Monophenols
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Nguyen HX, et al. Two new gingerol derivatives from the rhizome of Curcuma xanthorrhiza D.Dietr. Nat Prod Res. 2025 Sep 21:1-11. [Content Brief]

[2]. El-Halawany AM, et al. Protective effect of Aframomum melegueta phenolics against CCl₄-induced rat hepatocytes damage; role of apoptosis and pro-inflammatory cytokines inhibition. Sci Rep. 2014;4:5880. Published 2014 Jul 30. [Content Brief]

Calculators

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Concentration _(start) Concentration _(start)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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