B-Raf-IN-20
B-Raf-IN-20 (Compound Z-001) is a B-RAF inhibitor with an IC50 value of 37.80 nM. B-Raf-IN-20 binds to DFG-out/C-helix-in conformation in the B-RAF kinase. B-Raf-IN-20 has anti-cancer activity against non-small cell lung cancer.
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- 화학식: C34H37F3N4O4
- 분자량:622.68
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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B-Raf 37.80 nM (IC50) |
Chemical Information
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분자량 622.68
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화학식 C34H37F3N4O4
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SMILES
CC1=CC=C(NC(C2=CC(C(F)(F)F)=NC=C2)=O)C=C1C3=CC(N4CCOCC4)=NC(OC[C@]5(C6)C[C@@H]7C[C@H](C5)C[C@@]6(O)C7)=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)