TACC3-IN-3
TACC3-IN-3 is a TACC3 inhibitor. TACC3 is a scaffold protein that is highly expressed in various tumors and regulates microtubule/centrosome stability via phosphorylation by Aurora A. TACC3-IN-3 inhibits the proliferation of triple-negative breast cancer cells. TACC3-IN-3 is applicable to triple-negative breast cancer research.\n
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- CAS No.: 3115244-67-9
- 화학식: C25H27N5O
- 분자량:413.51
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Aurora Kinase Isoforms
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Biological Activity
TACC3-IN-3 (Compound 65) inhibits the proliferation of CAL-51 cells after 72 h, with a GI50 value of 0.31 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3115244-67-9
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분자량 413.51
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화학식 C25H27N5O
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SMILES
CN1C2=CC=C(C=C2N=C1)C3=CC=NC(NC4=CC(N5C[C@H](O[C@H](C5)C)C)=CC=C4)=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)