Tenidap sodium
Tenidap is a non-steroidal anti-inflammatory active molecule and a selective inhibitor of COX-1, with IC50 values of 0.03 μM for COX-1 and 1.2 μM for COX-2. Tenidap exhibits anti-inflammatory and anti-rheumatic effects. Tenidap is a specific inhibitor of SLC26A3.
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- CAS No.: 119784-94-0
- 화학식: C14H8ClN2NaO3S
- 분자량:342.73
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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COX-2 |
COX-1 |
Chemical Information
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CAS No. 119784-94-0
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분자량 342.73
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화학식 C14H8ClN2NaO3S
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SMILES
O=C1/C(C2=CC(Cl)=CC=C2N1C(N)=O)=C(C3=CC=CS3)\O[Na]
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Synonyms
CP-66248 sodium
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101. [Content Brief]
[2]. Blackburn WD Jr, et al. Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone. Arthritis Rheum. 1995 Oct;38(10):1447-56. [Content Brief]
[3]. Chávez JC, et al. Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation. Biol Reprod. 2012 Jan 19;86(1):1-14. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tenidap sodium Related Classifications
HY-105028A Related Classifications
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