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Cat. No.: HY-163998

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TLR4-IN-1

TLR4-IN-1 (compound 3k) inhibits the cell viability of RAW264.7 with an IC₅₀ of 1.02 μM. TLR4-IN-1 inhibits the release of cytokine TNF-α, IL-1β and IL-6, and exhibits anti-inflammatory efficacy in rats rheumatoid arthritis models.

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CAS No.: 2617578-93-3
화학식: C₁₀H₁₂O₄
분자량:196.20

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

TLR4-IN-1 Chemical Structure

CAS No.: 2617578-93-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Toll-like Receptor (TLR) Isoforms :

Chemical Information

CAS No. 2617578-93-3
분자량 196.20
화학식 C₁₀H₁₂O₄
SMILES

O=C1C(C(C)CC1C(CC(C)=O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhou S, et al., Design, Synthesis, and Antirheumatoid Arthritis Mechanism of TLR4 Inhibitors. ACS Omega. 2024 Aug 14;9(34):36232-36241. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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TLR4-IN-1

All Toll-like Receptor (TLR) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

TLR4-IN-1 Related Classifications

HY-163998 Related Classifications