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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
INF
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "INF" in MCE Product Catalog:
11
11 Cited Publications
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INF39 is an irreversible and noncytotoxic NLRP3 inhibitor.
Cat. No.: HY-P10152
CAS No.: 185462-59-3
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Cat. No.: HY-P5307
Synonyms: INF7-A5K-TAT
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Cat. No.: HY-P99252
CAS No.: 1116433-11-4
Synonyms: Anti-Human CD6 Recombinant Antibody
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Cat. No.: HY-164304
CAS No.: 1211379-56-4
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INF 195 is an NLRP3 inhibitor. INF 195 can inhibit NLRP3 driven macrophage pyroptosis and IL-1β release, with an EC50 value of 0.15 μM. INF 195 can reduce the infarct size of isolated mouse hearts at low doses, effectively preventing myocardial ischemia/reperfusion injury .
Cat. No.: HY-177094
CAS No.: 2489430-53-5
Synonyms: INF056
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Izicopan (INF056) is a complement factor C5a receptor (C5aR1) antagonist. Izicopan inhibits C5a-induced calcium mobilization with an IC50 of 10-100 nM. Izicopan is applicable for the research of complement-mediated inflammatory responses .
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INF4E is a potent NLRP3 inflammasome inhibitor. INF4E inhibits caspase-1 and NLRP3 ATPase activities. INF4E shows protection against the IR-induced myocardial injury and dysfunction .
Cat. No.: HY-P11000
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Cat. No.: HY-155517
CAS No.: 3049730-43-7
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INF200 (compound 5) is a sulfonylurea-based inhibitor of NLRP3 and NLRP3-mediated pyroptosis. INF200 has beneficial cardiometabolic effects in rat model of high-fat diet (HFD)-induced metaflammation，and shows anti-inflammatory activity to (10 μM) decreases IL-1β release in human macrophages. INF200 improves glucose and lipid profiles，and attenuates systemic inflammation and biomarkers of cardiac dysfunction (particularly BNP). INF200 also improves myocardial damage-dependent ischemia/reperfusion injury (IRI) in hemodynamic evaluation .
Cat. No.: HY-P10999
Synonyms: P55
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Cat. No.: HY-P5307A
Synonyms: INF7-A5K-TAT acetate
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Cat. No.: HY-N2838
CAS No.: 87827-55-2
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Cat. No.: HY-P10918
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Cat. No.: HY-163364
CAS No.: 945170-74-1
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DS-22-inf-021 is a neuraminidase (NA) inhibitor. DS-22-inf-021 has antiviral activity against influenza viruses .
Cat. No.: HY-146293
CAS No.: 2411955-43-4
HDAC6/HSP90-IN-1 (compound 17) is a potent and selective dual inhibitor of HDAC6 and HSP90, with IC50 values of 4.3 and 46.8 nM, respectively. HDAC6/HSP90-IN-1 down-regulates PD-L1 expression in INF-γ treated H1975 lung cancer cells. HDAC6/HSP90-IN-1 inhibits tumor growth in human H1975 xenograft mice .
Cat. No.: HY-W107077
CAS No.: 4993-87-7
INF55 is a NoA multidrug resistance pump inhibitor with the activity of inhibiting the NoA pump. The heterocomplex formed by INF55 combined with berberine shows the potential to combat the resistance of bacterial compounds. INF55 can enhance the antibacterial activity of berberine by reducing its efflux. The structural variants of INF55 can show different NoA inhibitory activities, thereby affecting the antibacterial effect of its corresponding heterocomplexes. Different derivatives of INF55 show similar activity in terms of antibacterial dose and effectiveness .
Cat. No.: HY-RS06806
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INF2 Human Pre-designed siRNA Set A contains three designed siRNAs for INF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24356
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Inf2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Inf2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01999
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CBLIF Human Pre-designed siRNA Set A contains three designed siRNAs for CBLIF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-153276
CAS No.: 1391944-16-3
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Androgen receptor-IN-5 is an androgen receptor inhibitor with potent anticancer effects. Androgen receptor-IN-5 also inhibits the production of IL-17A, IL- 17F and INF-γ (WO2023281097A1,Example 1/1) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
