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Cat. No.: HY-177094

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Izicopan

(Synonyms: INF056)

Izicopan (INF056) is a complement factor C5a receptor antagonist. Izicopan inhibits C5a-induced calcium mobilization with an IC₅₀ of 10-100 nM.

For research use only. We do not sell to patients.

CAS No.: 2489430-53-5
Formula: C₃₃H₃₁F₈N₃O₂
Molecular Weight:653.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Izicopan Chemical Structure

CAS No.: 2489430-53-5

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Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Izicopan (INF056) is a complement factor C5a receptor antagonist. Izicopan inhibits C5a-induced calcium mobilization with an IC₅₀ of 10-100 nM^[1].

Chemical Information

CAS No. 2489430-53-5
Molecular Weight 653.61
Formula C₃₃H₃₁F₈N₃O₂
SMILES

O=C(C1=C(C=CC=C1F)F)N2[C@@H](C3=CC=C(C=C3)NC4CCCC4)[C@H](C[C@H](C2)C(F)(F)F)C(NC5=CC(C(F)(F)F)=C(C=C5)C)=O
Synonyms

INF056
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yong Li, et al. Fused piperidinyl bicyclic and related compounds as modulators of c5a receptor. Patent. WO2020182384

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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