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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
ManNAc
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "ManNAc" in MCE Product Catalog:
Category:
Human Gut Microbiota Metabolites Natural Products Neurological Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W040154
CAS No.: 7772-94-3
Synonyms: Cyclic ManNAc
Category:
Microorganisms Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides
Target:
Cat. No.: HY-160821A
CAS No.: 335275-62-2
Synonyms: ManNAc-6P sodium salt
Target:
Research Areas:
N-Acetylmannosamine 6-phosphate sodium salt is a NanR modulator and an intermediate in the sialic acid pathway. N-Acetylmannosamine 6-phosphate sodium salt disrupts the binding of NanR to the promoter regions of nanAT and nanE, and prevents NanR-mediated transcriptional repression of these loci. N-Acetylmannosamine 6-phosphate sodium salt acts as a key precursor for sialic acid biosynthesis, participating in this process via Neu5Ac-9-P synthase. N-Acetylmannosamine 6-phosphate sodium salt can be used in research related to GNE myopathy .
Cat. No.: HY-128850S1
CAS No.: 875654-27-6
Synonyms: N-Acetylmannosamine-13C; ManNAc-13C
Research Areas:
N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal)) is a rate-limiting enzyme in bacteria metabolism that catalyzes the reversible aldol cleavage of sialic acid, and it regulates the overall metabolism of the bacterial sialic acid catabolic pathway. N-Acetylneuraminate lyase (CgNal) catalyzes the reversible condensation reaction of pyruvate and N-acetyl-d-mannosamine (ManNAc) to produce sialic acid N-acetylneuraminic acid (Neu5Ac). The protein expression of N-Acetylneuraminate lyase is downregulated at the translational level under the regulation of methyl methanesulfonate, and this change significantly impairs the adhesion and invasion abilities of bacteria to eukaryotic cells. N-Acetylneuraminate lyase is a key virulence-related protein in various pathogenic bacteria and is considered an antibiotic drug target. N-Acetylneuraminate lyase (CgNal) can be used in studies of invasive (extraintestinal) infectious diseases, Crohn's disease, and methicillin-resistant Staphylococcus aureus infections .
Cat. No.: HY-W040154R
CAS No.: 7772-94-3
Synonyms: Cyclic ManNAc (Standard)
Category:
Cat. No.: HY-128850S5
Synonyms: N-Acetylmannosamine-15N; ManNAc-15N
Cat. No.: HY-128850R
CAS No.: 3615-17-6
Synonyms: N-Acetylmannosamine (Standard); ManNAc (Standard)
Cat. No.: HY-128850S2
Synonyms: N-Acetylmannosamine-13C-1; ManNAc-13C-1
Cat. No.: HY-E70621
Research Areas:
Sialic acid aldolase (Pm NaNa) (EC 4.1.3.3) is a type I aldolase that catalyze the reversible aldol cleavage of N-acetylneuraminic acid (Neu5Ac) to form pyruvate and N-acetyl-D-mannosamine (ManNAc) with the equilibrium favoring the Neu5Ac cleavage .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
