875654-27-6
875654-27-6
Chemical Structure
N-Acetyl-D-mannosamine-13C
Synonym(s): N-Acetylmannosamine-13C; ManNAc-13C
- CAS No.: 875654-27-6
- Formula:C713CH15NO6
- Molecular Weight:222.20
InChIKey: MBLBDJOUHNCFQT-IOAKINAPSA-N
SMILES: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H]([13CH]=O)NC(C)=O
Biological Activity: N-Acetyl-D-mannosamine-13C is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Acetyl-D-mannosamine-13C | 99.00% | N-Acetyl-D-mannosamine-13C is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA) | ||||||||||||||||||||
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N-Acetyl-D-mannosamine (Standard) | 99.97% | N-Acetyl-D-mannosamine (Standard) is an analytical standard for N-Acetyl-D-mannosamine. This product is intended for research and analytical applications. N-Acetyl-D-mannosamine (ManNAc) is an orally active sialic acid (Sialic Acid) precursor that can prevent hypertension by increasing sialylation of IgG and has potential for use in cardiovascular disease research. N-Acetyl-D-mannosamine activates hypocretin (HCRT) gene expression and alters | ||||||||||||||||||||
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N-Acetyl-D-mannosamine-15N | N-Acetyl-D-mannosamine-15N is the 15N labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA) | |||||||||||||||||||||
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N-Acetyl-D-mannosamine-13C-1 | N-Acetyl-D-mannosamine-13C-1 is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA) | |||||||||||||||||||||
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N-Acetyl-D-mannosamine | 99.94% | N-Acetyl-D-mannosamine (ManNAc) is an oral active sialic acid precursor that can prevent hypertension by increasing sialylation of IgG, making it a promising candidate for cardiovascular disease research. Additionally, N-Acetyl-D-mannosamine can activate hypocretin (HCRT) gene expression in orexin neurons and improve neurodegeneration caused by aging, offering potential avenues for research in neurological disorders. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Revilla-Nuin B, et al. Transport of N-acetyl-D-mannosamine and N-acetyl-D-glucosamine in Escherichia coli K1: effect on capsular polysialic acid production. FEBS Lett. 2002 Jan 30;511(1-3):97-101.;Hayakawa K, et al. Reactivation of hyperglycemia-induced h [Content Brief]
