Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
18:1 PI
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "18:1 PI" in MCE Product Catalog:
2
2 Cited Publications
FzM1.8, derives from FzM1, is an allosteric agonist of FZD4 with pEC50 of 6.4. FzM1.8 binds to FZD4 and activates the WNT/β-catenin pathway, by promoting TCF/LEF transcriptional activity in the absence of any WNT ligand. FzM1.8 stabilizes FZD4 with an increased affinity for heterotrimeric G protein and stimulates the release of the Gβγ subunit that in turn activates PI3K .
1
1 Cited Publications
Cat. No.: HY-NP181
Category:
Alkaloids Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Cancer
Target:
Cat. No.: HY-157704
CAS No.: 1246303-09-2
Cat. No.: HY-157706
CAS No.: 799268-54-5
Target:
Research Areas:
PI(3,4)P2 (18:1) ammonium salt is a phosphatidylinositol 3 kinase (PI3K) activator. PI(3,4)P2 (18:1) ammonium salt is a polyphosphorylated phosphatidylinositol that promotes the activation of AKT (protein kinase B) by activating PI3K, which affects cell metabolism, growth and survival. PI(3,4)P2 (18:1) ammonium salt is also involved in regulating dynamic changes in the cytoskeleton, affecting cell morphology and movement. PI(3,4)P2 (18:1) ammonium salt can be used in research on the development of cancer, diabetes and cardiovascular disease .
Synonyms: 1,2-Dioleoyl-sn-glycero-3-phospho-1′-myo-inositol-4′,5′-bisphosphate ammonium
0 Images
D-myo-Inositol, 1-[(2R)-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propyl hydrogen phosphate] 4-(dihydrogen phosphate)
Cat. No.: HY-157701
CAS No.: 1803104-55-3
Cat. No.: HY-178923
Target:
Research Areas:
NNRT-IN-14 is an HIV-1 reverse transcriptase inhibitor (IC50 = 0.175 µM). NNRT-IN-14 can form hydrogen bonds with LYS101, PRO225, and PHE227, and π–π stacking with TYR181 and TRP229. NNRT-IN-14 can be used for the study of HIV .
0 Images
D-myo-Inositol, 1-[(2R)-2-hydroxy-3-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:1)
Cat. No.: HY-W725832
CAS No.: 1246298-13-4
Synonyms: PI(18:1(9Z)/0:0) ammonium
Cat. No.: HY-157707
CAS No.: 799268-57-8
0 Images
D-myo-Inositol, 1-[(2R)-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:1)
Cat. No.: HY-157709
CAS No.: 799268-53-4
Synonyms: DOPI(18:1(9Z)/18:1(9Z)) ammonium
Cat. No.: HY-146824S
CAS No.: 2342575-35-1
Cat. No.: HY-N15977
CAS No.: 2260670-01-5
Category:
Target:
0 Images
D-myo-Inositol, 1-[(2R)-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propyl hydrogen phosphate] 3,5-bis(dihydrogen phosphate), ammonium salt (1:3)
Cat. No.: HY-157705
CAS No.: 799268-55-6
Synonyms: PIP2[3',5'](18:1(9Z)/18:1(9Z)) triammonium
Cat. No.: HY-10109A
Research Areas:
AS-605240 (potassium) is an orally active PI3Kγ inhibitor (IC50: 8 nM; Ki: 7.8 nM). AS-605240 (potassium) inhibits MCP-1- and CSF1-induced PKB phosphorylation (IC50 values are 0.181 and 0.550 µM, respectively). AS-605240 (potassium) reduces neutrophil recruitment in RANTES (CCL5)- and thioglycolate-induced peritonitis mouse models (EC50 values are 9.1 and 10 mg/kg, respectively). AS-605240 (potassium) ameliorates αCII-IA-induced arthritis in mice .
Cat. No.: HY-W725804
CAS No.: 2410279-92-2
Target:
Research Areas:
15:0-18:1 PI (ammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.
0 Images
D-myo-Inositol, 4-(dihydrogen phosphate) 1-[(2R)-3-[(1-oxohexadecyl)oxy]-2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propyl hydrogen phosphate], ammonium salt (1:2)
Cat. No.: HY-157621
CAS No.: 2260795-75-1
Cat. No.: HY-N16001
CAS No.: 2260670-03-7
Category:
Target:
Cat. No.: HY-157619
CAS No.: 50730-13-7
Synonyms: 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol ammonium
Target:
Research Areas:
16:0-18:1 PI (ammonium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.
Cat. No.: HY-L181
29,828 compounds
Bioactive small molecules are important sources of lead compounds and effective tools for drug screening. Because the target of active small molecules is clear, it is conducive to the study of mechanism. In addition, due to the large structural differences between the individual active molecules, it is easier to obtain a greater variety of lead compounds.
MCE integrates the Bioactive Compound Library (HY-L001) and Novel Bioactive Compound Library (HY-L111) to form the Bioactive Compound Library Max. Bioactive Compound Library Max contains novel active small molecules, molecules that have entered the clinical stage and the market, and small molecules that have been verified by cell experiments or biochemical experiments, which fundamentally expands the number of compound libraries in the library and improves the structural diversity, and is an effective tool to start drug screening and mechanism research.
MCE can provide a library of 29,828 mitophagy compounds, which can be used for drug development and mechanism research in cancer, immunity, infection and other hot research fields.
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
