1 Result for "

373370-73-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "373370-73-1" in MCE Product Catalog:

Cat. No.: HY-122658
CAS No.: 373370-73-1
Synonyms: MB-1
Research Areas:  

Metabolic Disease

MitoBloCK-1 (MB-1) is an inhibitor that blocks the import of substrates that use the TIM22 import pathway. MitoBloCK-1 inhibits import by preventing binding of substrate to tim9/10 complex to the substrate, thus the substrate failed to be reach the TIM22 translocon. MitoBloCK-1 inhibits protein import of TIM22 substrates into mitochondria. MitoBloCK-1 attenuates the import of the carrier proteins including the ADP/ATP and phosphate carriers. MitoBloCK-1 also inhibits the import of an additional carrier protein, PiC, and the outer membrane protein Tom40 .
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