1 Result for "

4099-30-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "4099-30-3" in MCE Product Catalog:

Cat. No.: HY-N0882
CAS No.: 4099-30-3
Synonyms: Deacetylcinobufotalin
Desacetylcinobufotalin is an active component isolated from Venenum Bufonis, which exhibits significant cytotoxicity against human hepatocellular carcinoma HepG2 cells (IC50 = 0.0279 µmol/mL). Desacetylcinobufotalin upregulates Bax protein expression, downregulates Bcl-2 protein expression, and induces apoptosis via the mitochondrial pathway. Desacetylcinobufotalin inhibits cancer cell survival, and shows lower cytotoxicity compared to its parent compound Cinobufagin (HY-N0421). Desacetylcinobufotalin can be used in hepatocellular carcinoma-related research .
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