7 Results for "

786-0 cells

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "786-0 cells" in MCE Product Catalog:

Cat. No.: HY-P99161
CAS No.: 2226775-26-2
Synonyms: BGB149

Target:  

TAM Receptor

Research Areas:  

Cancer

Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas .
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Cat. No.: HY-15960
CAS No.: 1246203-32-6
Synonyms: VDC-597 free base
Target:  

PI3K mTOR Apoptosis

Research Areas:  

Cancer

PWT-33597 (VDC-597) free base is a dual inhibitor of PI3Kα and mTOR, which can effectively block the signaling downstream of PI3K and mTOR. PWT-33597 free base is capable of inducing tumor cell apoptosis and inhibiting tumor growth. PWT-33597 free base has anti-tumor activity and can be used in the research of tumors such as renal cell carcinoma .
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Cat. No.: HY-15960A
CAS No.: 1246203-36-0
Synonyms: VDC-597; SN33597
Target:  

PI3K mTOR Apoptosis

Research Areas:  

Cancer

PWT-33597 (VDC-597) is a dual inhibitor of PI3Kα and mTOR, which can effectively block the signaling downstream of PI3K and mTOR. PWT-33597 is capable of inducing tumor cell apoptosis and inhibiting tumor growth. PWT-33597 has anti-tumor activity and can be used in the research of tumors such as renal cell carcinoma .
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Cat. No.: HY-155271
Target:  

Carbonic Anhydrase

Research Areas:  

Others

hCAXII-IN-7 (compound 6e) is a hCA XII inhibitor. hCAXII-IN-7 has BBB permeability. hCAXII-IN-7 induces 786-0, SF-539 and HS 578 T cells apoptotic .
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Cat. No.: HY-169476
CAS No.: 3140-51-0
Target:  

Drug Derivative

Research Areas:  

Cancer

Pyrrolidine linoleamide is a derivative of linoleic acid amide with anticancer activity. Pyrrolidine linoleamide exhibits antiproliferative activity against a range of cancer cell lines, with IC50 values of 12.0, 27.5, 7.7, 21.9, 36.6, 32.6, and 33.9 μg/mL against U251, MCF-7, NCI-ADR/RES, 786-0, NCI-H460, PC-3, and OVCAR-3 cell lines, respectively .
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Cat. No.: HY-151341
CAS No.: 2827693-99-0
Research Areas:  

Cancer

HIF-1/2α-IN-1 is an orally active HIF-2α inhibitor. HIF-1/2α-IN-1 inhibits HIF-2α activity with an IC50 value of 0.92 μM. HIF-1/2α-IN-1 also can decrease HIF-1α levels. HIF-1/2α-IN-1 can be used for the research of clear cell renal cell carcinoma (ccRCC) .
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Cat. No.: HY-N10621
CAS No.: 108352-70-1
3,5-Dimethoxy-2,7-phenanthrenediol (compound 2) is a phenanthrene compound isolated from the roots of Combretum laxum. 3,5-Dimethoxy-2,7-phenanthrenediol is cytotoxic to human cancer cell lines 786-0, MCF-7 and NCI/ADR-RES, with IC50s of 73.26 μM, 118.40 μM and 83.99 μM respectively. 3,5-Dimethoxy-2,7-phenanthrenediol also has free radical scavenging activity with an IC50 of 20.4 μM .
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