2827693-99-0
2827693-99-0
Chemical Structure
HIF-1/2α-IN-1
- CAS No.: 2827693-99-0
- Formula:C17H16N6O4
- Molecular Weight:368.35
IUPAC Name: 5-(3,4-dimethoxyphenyl)-N-(4-methoxy-1H-imidazo[4,5-c]pyridin-2-yl)-1,3,4-oxadiazol-2-amine
InChIKey: XDRGZNHVBJAQGG-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1OC)C2=NN=C(O2)NC3=NC4=C(N3)C=CN=C4OC
Biological Activity: HIF-1/2α-IN-1 is an orally active HIF-2α inhibitor. HIF-1/2α-IN-1 inhibits HIF-2α activity with an IC50 value of 0.92 μM. HIF-1/2α-IN-1 also can decrease HIF-1α levels. HIF-1/2α-IN-1 can be used for the research of clear cell renal cell carcinoma (ccRCC) [1].
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HIF-1/2α-IN-1 | HIF-1/2α-IN-1 is an orally active HIF-2α inhibitor. HIF-1/2α-IN-1 inhibits HIF-2α activity with an IC50 value of 0.92 μM. HIF-1/2α-IN-1 also can decrease HIF-1α levels. HIF-1/2α-IN-1 can be used for the research of clear cell renal cell carcinoma (ccRCC) . | |||||||||||||||||||||
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References
Keywords
