1246203-36-0
Chemical Structure
PWT-33597
Synonym(s): VDC-597; SN33597
- CAS No.: 1246203-36-0
- Formula:C27H34F2N8O7S2
- Molecular Weight:684.74
IUPAC Name: N-(4-(4-(2-(difluoromethyl)-4-methoxy-1H-benzo[d]imidazol-1-yl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-2-(dimethylamino)ethane-1-sulfonamide methanesulfonate
InChIKey: XSLUGEGXPCDRTN-UHFFFAOYSA-N
SMILES: CN(CCS(=O)(NC1=CC=C(C2=NC(N3C4=CC=CC(OC)=C4N=C3C(F)F)=NC(N5CCOCC5)=N2)C=C1)=O)C.CS(O)(=O)=O
Biological Activity: PWT-33597 (VDC-597) is a dual inhibitor of PI3Kα and mTOR, which can effectively block the signaling downstream of PI3K and mTOR. PWT-33597 is capable of inducing tumor cell apoptosis and inhibiting tumor growth. PWT-33597 has anti-tumor activity and can be used in the research of tumors such as renal cell carcinoma[1].
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PWT-33597 | PWT-33597 (VDC-597) is a dual inhibitor of PI3Kα and mTOR, which can effectively block the signaling downstream of PI3K and mTOR. PWT-33597 is capable of inducing tumor cell apoptosis and inhibiting tumor growth. PWT-33597 has anti-tumor activity and can be used in the research of tumors such as renal cell carcinoma. | |||||||||||||||||||||
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Keywords
