2226775-26-2
2226775-26-2
Chemical Structure
Tilvestamab
Synonym(s): BGB149
- CAS No.: 2226775-26-2
- Formula:N/A
- Molecular Weight:(146.16 kDa)
SMILES: [Tilvestamab]
Biological Activity: Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tilvestamab | 98.08% | Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas. | ||||||||||||||||||||
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