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80458-10-2

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Oganomycin GB
Oganomycin GB
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Cat. No.: HY-N14926
CAS No.: 80458-10-2
Category:  

Natural Products Microorganisms Ketones, Aldehydes, Acids

Target:  

Bacterial

Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB .
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