1 Result for "

A831

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "A831" in MCE Product Catalog:

Cat. No.: HY-123536
CAS No.: 944278-62-0
Synonyms: A-831
Target:  

PI4K HCV

Research Areas:  

Infection

AZD2836 (A-831) is a 4-aminopyrazolone compound with anti-HCV activity. AZD2836 inhibits the activity of the host cell kinase PI4KIIIα, causing metabolic disorder of the cell membrane component PI4P that is necessary for viral replication. In the HCV subgenomic replicon cell model, the EC50 values of AZD2836 for genotype 1b (Con1 strain) and genotype 1a (Lemon strain) are 270 nM and 550 nM, respectively .
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