15 Results for "

ACTRIIA

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "ACTRIIA" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99355
CAS No.: 1356922-05-8
Synonyms: Anti-ACVR2B Reference Antibody; BYM338

Target:  

TGF-β Receptor

Research Areas:  

Metabolic Disease

Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII), with KDs of 1.7 pM and 434 pM for human ActRIIB and ActRIIA, respectively. Bimagrumab can be used for the research of pathological muscle loss and weakness .
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1
1 Cited Publications
Cat. No.: HY-P99590A
Synonyms: RAP-011
Sotatercept (mIgG2a) (RAP-011), the murine homolog of Sotatercept (ACE-011) (HY-P99590), is a soluble activin receptor type IIA (ActRIIA) ligand trap. Sotatercept (mIgG2a) inhibits the binding of activin A and other members of the TGF-β superfamily (such as Activin A/B, GDF11 and BMP9/10) to their receptors by combining and neutralizing them, thereby regulating cell proliferation and differentiation. Sotatercept (mIgG2a) mainly inhibits the SMAD2/3 signaling pathway, and can be used in various diseases such as chronic kidney disease. Sotatercept (mIgG2a) reduces the expression of erythropoietic hepcidin (ERFE), regulates iron metabolism, and promotes red blood cell production. Sotatercept (mIgG2a) has a dual effect of promoting bone formation (anabolic) and inhibiting bone resorption (catabolic) .
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Cat. No.: HY-P991504
LAE-102 is the selective anti-ActRIIA (activin receptor type IIA or ACVR2) monoclonal antibody. LAE-102 increases muscle mass and reduces fat mass. LAE102 can increase serum activin A levels in vivo. LAE-102 is promising for research of obesity .
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Cat. No.: HY-RS00246
Research Areas:  

Others

Acvr2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acvr2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P703995
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
Species:  
Source:  
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Cat. No.: HY-P703977
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
Species:  
Source:  
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Cat. No.: HY-P703683
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-2A; Activin receptor type IIA; ACTR-IIA; Acvr2a; ACTR-IIA
Species:  
Rat
Source:  
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Cat. No.: HY-P705677
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-2A; Activin receptor type IIA; ACTR-IIA; Acvr2a; ACTR-IIA
Species:  
Source:  
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Cat. No.: HY-P705726
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-2A; Activin receptor type IIA (ACTR-IIA; ACTRIIA); ACVR2
Species:  
Source:  
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Cat. No.: HY-P75562
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2
Species:  
Source:  
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Cat. No.: HY-P75563
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2
Species:  
Source:  
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Cat. No.: HY-P75537
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2
Species:  
Source:  
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Cat. No.: HY-P83050
Synonyms: ACTR2; ACTRII; ACTRIIA; Acvr2; ACVR2A

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7455A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuActivin receptor type 2A, His; ACVR-2A; Activin receptor type 2A
Species:  
Source:  
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Cat. No.: HY-P7455
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuActivin receptor type 2A, His; ACVR-2A; Activin receptor type 2A
Species:  
Source:  
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