19 Results for "

ACVR2A Inhibitors

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "ACVR2A Inhibitors" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99355
CAS No.: 1356922-05-8
Synonyms: Anti-ACVR2B Reference Antibody; BYM338

Target:  

TGF-β Receptor

Research Areas:  

Metabolic Disease

Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII), with KDs of 1.7 pM and 434 pM for human ActRIIB and ActRIIA, respectively. Bimagrumab can be used for the research of pathological muscle loss and weakness [2].
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2
2 Cited Publications
Cat. No.: HY-P99590
CAS No.: 1001080-50-7
Synonyms: ACE-011; MK-7962
Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions [2] .
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Cat. No.: HY-RS00246
Research Areas:  

Others

Acvr2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acvr2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990326
Synonyms: Ab-14E1

Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

Anti-ACVR2A Antibody (Ab-14E1) is a CHO-expressed human antibody that targets ACVR2A. Anti-ACVR2A Antibody (Ab-14E1) features an IgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-ACVR2A Antibody (Ab-14E1) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS00245
Research Areas:  

Others

ACVR2A Human Pre-designed siRNA Set A contains three designed siRNAs for ACVR2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS00247
Research Areas:  

Others

Acvr2a Rat Pre-designed siRNA Set A contains three designed siRNAs for Acvr2a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174783
Target:  

mRNA

Research Areas:  

Cancer

Human ACVR2A mRNA encodes the human activin A receptor type 2A (ACVR2A) protein, a member of the TGFB family. ACVR2A mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. It may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality.
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Cat. No.: HY-P991158
CAS No.: 2996105-98-5

Target:  

TGF-β Receptor

Research Areas:  

Neurological Disease

Rinvatercept, a fusion protein, is a glycyl (1)-chimeric N-terminal (1-108)-peptide (2-109) combined from the sequences of the extracellular domains of the human ACVR2A/B, and is fused via a G3 peptide linker (110-112) to an immunoglobulin G1 (IgG1) Fc fragment. Rinvatercept can be used for research of neuromuscular disease .
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Cat. No.: HY-P703977
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
Species:  
Source:  
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Cat. No.: HY-P703995
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
Species:  
Source:  
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Cat. No.: HY-P83050
Synonyms: ACTR2; ACTRII; ACTRIIA; ACVR2; ACVR2A

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P703683
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-2A; Activin receptor type IIA; ACTR-IIA; ACVR2A; ACTR-IIA
Species:  
Rat
Source:  
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Cat. No.: HY-P705677
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-2A; Activin receptor type IIA; ACTR-IIA; ACVR2A; ACTR-IIA
Species:  
Source:  
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Cat. No.: HY-P75563
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2
Species:  
Source:  
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Cat. No.: HY-P75537
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2
Species:  
Source:  
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Cat. No.: HY-P75562
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR-2A; Activin receptor type 2A; ACTR-IIA; ACVR2
Species:  
Source:  
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Cat. No.: HY-P7455A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuActivin receptor type 2A, His; ACVR-2A; Activin receptor type 2A
Species:  
Source:  
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Cat. No.: HY-P7455
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuActivin receptor type 2A, His; ACVR-2A; Activin receptor type 2A
Species:  
Source:  
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Cat. No.: HY-P705726
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type-2A; Activin receptor type IIA (ACTR-IIA; ACTRIIA); ACVR2
Species:  
Source:  
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