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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
APN Inhibitors
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "APN Inhibitors" in MCE Product Catalog:
12
Target:
12
12 Publications Verification
Cat. No.: HY-B0134A
CAS No.: 65391-42-6
Synonyms: Ubenimex hydrochloride
Target:
Cat. No.: HY-P9933
CAS No.: 1363687-32-4
Synonyms: APN-311; Ch14.18; MAb-14.18
Cat. No.: HY-B0134AS
Synonyms: Ubenimex-d7 hydrochloride
Cat. No.: HY-N2150
CAS No.: 110659-91-1
Cat. No.: HY-B0134R
CAS No.: 58970-76-6
Synonyms: Ubenimex (Standard)
Category:
Cat. No.: HY-116306
CAS No.: 123652-87-9
Category:
Target:
Cat. No.: HY-P11642A
Research Areas:
Cat. No.: HY-145244
CAS No.: 2854340-31-9
APN/AKT-IN-1 is a potent and dual inhibitor of APN and AKT with IC50s of 0.21 and 0.27 μM, respectively. APN/AKT-IN-1 can effectively inhibit the phosphorylation of GSK3β, the intracellular substrate of AKT .
Cat. No.: HY-170962
Target:
Research Areas:
SDUY817 is a dual APN/NEP inhibitor, with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. SDUY817 exerts analgesic effects in a concentration- and time-dependent manner, and can be used for research in the field of neuropathic pain disorders .
Cat. No.: HY-172879
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Research Areas:
Aminopeptidase N inhibitor 2 (Compound 2k) is an APN inhibitor (IC50: 4.3 μM) and has antitumor activity.
Cat. No.: HY-B0134B
CAS No.: 223763-80-2
Synonyms: Ubenimex trifluoroacetate
Target:
Cat. No.: HY-170961
Target:
Research Areas:
SDUY816 is an oral active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. SDUY816 exhibits analgesic effects and demonstrates good safety and pharmacokinetic profiles, with an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral administration, 10 mg/kg). SDUY816 has potential applications in the research of neuropathic pain disorders .
Cat. No.: HY-B0134AR
CAS No.: 65391-42-6
Synonyms: Ubenimex hydrochloride (Standard)
Category:
Cat. No.: HY-B0134S1
Synonyms: Ubenimex-d10
Cat. No.: HY-P11642
CAS No.: 131748-26-0
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
