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SDUY816

SDUY816 is an oral active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. SDUY816 exhibits analgesic effects and demonstrates good safety and pharmacokinetic profiles, with an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral administration, 10 mg/kg). SDUY816 has potential applications in the research of neuropathic pain disorders.

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  • Formel: C18H16IN3O3
  • Molecular Weight:449.24
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • SDUY816 Chemical Structure
    SDUY816 Chemical Structure
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  • SDUY816 Chemical Structure
    SDUY816 Chemical Structure
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  • SDUY816