5 Results for "

ATF4-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "ATF4-IN-1" in MCE Product Catalog:

Cat. No.: HY-158201
CAS No.: 2991057-76-0
Purity:  99.29%
ATF4-IN-1 (Compound 21) is an ATF4 inhibitor and also an eIF2B activator. ATF4-IN-1 can be used in research on neurodegenerative diseases .
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Cat. No.: HY-100355
CAS No.: 2304-81-6
Purity:  99.95%
Synonyms: C18-Ceramide
C18-Ceramide (d18:1/18:0) is a bioactive molecule with multiple functions in cells, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology .
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Cat. No.: HY-W020952
CAS No.: 14024-61-4
Synonyms: Palladium(Ⅱ) 2,4-pentanedionate; Pd(acac)2
Palladium(II) acetylacetonate is a metal-organic complex. Palladium(II) acetylacetonate upregulates the expression of GRP78, ATF-4, XBP-1, CHOP, and phosphorylated c-Jun. Palladium(II) acetylacetonate induces Apoptosis. Palladium(II) acetylacetonate has anticancer effects against non-small cell lung cancer, gastric cancer, leukemia, and cervical cancer .
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Cat. No.: HY-158205
CAS No.: 1895934-61-8
Synonyms: 4-Hydroperoxy-2-decenoic acid ethyl ester
HPO-DAEE (4-Hydroperoxy-2-decenoic acid ethyl ester) elicits nuclear accumulation of Nrf2 and activated antioxidant response element (ARE). HPO-DAEE induces antioxidant genes upregulation (eg: HO-1) through Nrf2-ARE signaling. HPO-DAEE induces reactive oxygen species generation. HPO-DAEE also inhibits histone deacetylase and upregulate expression of extracellular superoxide dismutase via histone acetylation. HPO-DAEE protects against 6-hydroxydopamine-induced cell death via activation of Nrf2-ARE and eIF2α-ATF4 pathways .
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Cat. No.: HY-171438
CAS No.: 2144475-18-1
Research Areas:  

Others

ATF4 agonist 1 (Compound 298) is a ATF4 agonist and integrated stress pathway modulator .
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