9 Results for "

Adefovir

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Adefovir" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-108917
CAS No.: 1092970-12-1
Purity:  99.79%
Synonyms: GLS4
Target:  

HBV

Research Areas:  

Infection

Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir (HY-B1826)-resistant HBV with an IC50 of 12 nM.
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2
2 Cited Publications
Cat. No.: HY-B0255
CAS No.: 142340-99-6
Synonyms: GS 0840
Adefovir dipivoxil is an orally active adenosine analog and Adefovir prodrug. Adefovir dipivoxil inhibits DNA synthesis, activates the ATR signaling pathway, and disrupts the KCTD12-CDK1 interaction. Adefovir dipivoxil has antiviral activity against PRV, HBV, and orthopoxviruses. Adefovir dipivoxil has inhibitory effects on both lamivudine-resistant and wild-type strains. Adefovir dipivoxil has antitumor activity against lung and colon cancer .
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2
2 Cited Publications
Cat. No.: HY-B1826
CAS No.: 106941-25-7
Synonyms: GS-0393; PMEA
Research Areas:  

Infection

Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses .
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Cat. No.: HY-B0255R
CAS No.: 142340-99-6
Synonyms: GS 0840 (Standard)
Adefovir dipivoxil (Standard) is the analytical standard of Adefovir dipivoxil. This product is intended for research and analytical applications. Adefovir dipivoxil is an orally active adenosine analog and Adefovir prodrug. Adefovir dipivoxil inhibits DNA synthesis, activates the ATR signaling pathway, and disrupts the KCTD12-CDK1 interaction. Adefovir dipivoxil has antiviral activity against PRV, HBV, and orthopoxviruses. Adefovir dipivoxil has inhibitory effects on both lamivudine-resistant and wild-type strains. Adefovir dipivoxil has antitumor activity against lung and colon cancer .
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Cat. No.: HY-B1826S2
CAS No.: 1190021-70-5
Synonyms: GS-0393-d4; PMEA-d4
Adefovir-d4 is the deuterium labeled Adefovir. Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses .
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Cat. No.: HY-W739906
CAS No.: 1189929-36-9
Adefovir Diethyl Ester-d4 is the deuterium labeled Diethyl ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonate (HY-W330007).
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Cat. No.: HY-108917A
CAS No.: 1646361-04-7
Synonyms: GLS4 mesylate
Target:  

HBV

Research Areas:  

Infection

Morphothiadin (GLS4) mesylate is a potent inhibitor of wild-type and Adefovir (HY-B1826)-resistant HBV replication with an IC50 value of 12 nM .
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Cat. No.: HY-168165
CAS No.: 129556-87-2
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Adefovir diphosphate is an antiviral compound with activity against hepatitis B virus (HBV). Adefovir diphosphate blocks the replication of HBV by inhibiting reverse transcriptase. Adefovir diphosphate has also shown activity against other viruses such as herpes viruses and human immunodeficiency virus. Adefovir diphosphate is used as an effective inhibitory option in the suppression of chronic hepatitis B. The mechanism of action of Adefovir diphosphate involves blocking the autophosphorylation of growth factor receptors, thereby potentially reducing the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B .
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Cat. No.: HY-108917R
CAS No.: 1092970-12-1
Synonyms: GLS4 (Standard)
Target:  

Reference Standards HBV

Research Areas:  

Infection

Morphothiadin (Standard) is the analytical standard of Morphothiadin (HY-108917). This product is intended for research and analytical applications. Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir (HY-B1826)-resistant HBV with an IC50 of 12 nM.
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