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Results for "

Ala-Ala-Ala

" in MedChemExpress (MCE) Product Catalog:

45

Inhibitors & Agonists

55

Peptides

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P4210
    Sulanemadlin
    1 Publications Verification

    ALRN-6924; MP-4897

    		 MDM-2/p53 Cancer
    Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research .
    Sulanemadlin
  • HY-P11303
    PADRE peptide

    		CD74 MHC Neurological Disease Cancer
    PADRE peptide is a pan-HLA-DR binding epitope and immunostimulant. PADRE peptide binds to the peptide-binding groove of MHC class II molecules for presentation to CD4 + T cells, thereby effectively stimulating specific immune responses. PADRE peptide not only enhances anti-tumor immune responses, inhibits tumor growth and prolongs survival; it also significantly increases the frequency of E7-specific CD8 + T cells and improves therapeutic efficacy against TC-1 tumors when used in combination with E7 peptide-based vaccines and poly (I:C). The intensity of the immune response induced by PADRE peptide is lower than that of the Ii-PADRE DNA vaccine, and it fails to enhance the immune effect of CRT-E7 DNA. PADRE peptide is widely applicable to research on related tumors such as melanoma, glioblastoma and cervical cancer .
    PADRE peptide
  • HY-P6312
    ESAT6 Epitope

    		MHC Inflammation/Immunology
    ESAT6 Epitope is a ESAT6 CD4 + T cell epitope. ESAT6 Epitope binds to MHC class I molecules with an IC50 value of approximately 180 nM. ESAT6 Epitope has weak immunogenicity. ESAT6 Epitope can be used in studies related to pulmonary tuberculosis .
    ESAT6 Epitope
  • HY-145237
    BM213
    3 Publications Verification

    		 Complement System Apoptosis Reactive Oxygen Species (ROS) Cancer
    BM213 is a selective C5aR agonist, with an EC50 of 59 nM. BM213 specifically activates the C5a-C5aR1 axis, which in turn promotes neutrophil extracellular trap (NET) formation and exacerbates inflammatory responses. BM213 significantly induces ventricular dilationin, promotes myocardial ROS production, and induces cardiomyocyte apoptosis in rats. BM213 can be used for the study of myocardial ischemia/reperfusion (I/R) injury .
    BM213
  • HY-P10218
    MANS peptide
    1 Publications Verification

    		 MARCKS PKC Inflammation/Immunology Cancer
    MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .
    MANS peptide
  • HY-P0263
    Dermaseptin

    		Bacterial Fungal Antibiotic Infection
    Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .
    Dermaseptin
  • HY-P1858A
    Urocortin III, mouse TFA

    		CRFR Cardiovascular Disease Neurological Disease Endocrinology
    Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2 . Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics .
    Urocortin III, mouse TFA
  • HY-P3106
    (Z-Ala-Ala-Ala-Ala)2Rh110

    (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-Alanyl-L-arginine amide Rhodamine 110

    		 Fluorescent Dye Others
    (Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.
    (Z-Ala-Ala-Ala-Ala)2Rh110
  • HY-P10218A
    MANS peptide TFA
    1 Publications Verification

    		 MARCKS PKC Inflammation/Immunology Cancer
    MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218). MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .
    MANS peptide TFA
  • HY-P1858
    Urocortin III, mouse

    		CRFR Cardiovascular Disease Neurological Disease Endocrinology
    Urocortin III, mouse is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2 . Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics .
    Urocortin III, mouse
  • HY-P3558
    Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met

    		Amino Acid Derivatives Others
    Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met
    Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met
  • HY-W013460
    Ala-Ala-Ala

    		Amino Acid Derivatives Others
    Ala-Ala-Ala is an alanine derivative .
    Ala-Ala-Ala
  • HY-P0305
    PrP (106-126)

    Prion protein (106-126)

    		 Prion Protein Infection
    PrP (106-126) is a peptide corresponding to the prion protein (PrP) amyloidogenic region, and its biochemical properties resemble the infectious form of prion protein.
    PrP (106-126)
  • HY-P3019
    Urocortin III (human)

    		CRFR Cardiovascular Disease Neurological Disease Endocrinology
    Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) preferentially binds and activates CRF-R2 and has a discrete central nervous system and peripheral distribution. Urocortin III (human) potently binds to type 2 CRF receptors, specifically mCRF2β (Ki = 13.5 nM) and rCRF2α (Ki = 21.7 nM), while demonstrating negligible affinity for hCRF1 (Ki >100 nM). Urocortin III (human) mediates somatostatin-dependent negative feedback control of Insulin (human) (HY-P0035) secretion [1][2].
    Urocortin III (human)
  • HY-P5594
    Dermaseptin-S1

    		Fungal Infection
    Dermaseptin-S1 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S1
  • HY-P4704A
    α-Synuclein (61-95) (human) TFA

    		α-synuclein Neurological Disease
    α-Synuclein (61-95) (human) TFA is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) TFA can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .
    α-Synuclein (61-95) (human) TFA
  • HY-P3019A
    Urocortin III (human) TFA

    		CRFR Cardiovascular Disease Neurological Disease Metabolic Disease
    Urocortin III (human) TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) TFA preferentially binds and activates CRF-R2 and has a discrete central nervous system and peripheral distribution. Urocortin III (human) TFA potently binds to type 2 CRF receptors, specifically mCRF2β (Ki = 13.5 nM) and rCRF2α (Ki = 21.7 nM), while demonstrating negligible affinity for hCRF1 (Ki >100 nM). Urocortin III (human) TFA mediates somatostatin-dependent negative feedback control of Insulin (human) (HY-P0035) secretion .
    Urocortin III (human) TFA
  • HY-P4350
    Suc-Ala-Ala-Ala-AMC

    		Elastase Others
    Suc-Ala-Ala-Ala-AMC is a peptide substrate of elastase or elastase-like .
    Suc-Ala-Ala-Ala-AMC
  • HY-P4353
    D-{Ala-Ala-Ala}

    		Bacterial Others
    D-{Ala-Ala-Ala} is a tripeptide. D-{Ala-Ala-Ala} binds to ristocetin to detect bacteria at low concentrations .
    D-{Ala-Ala-Ala}
  • HY-P10183
    CD36 Peptide P (139-155), Cys conjugated

    Cys-CD36(139-155)

    		 Transmembrane Glycoprotein Inflammation/Immunology
    CD36 Peptide P (139-155), Cys conjugated is a Cys labelled CD36 Peptide, and can inhibit the immunoadsorption of CD36 by OKM5 .
    CD36 Peptide P (139-155), Cys conjugated
  • HY-P11219
    TAT-PDHPS1

    		YAP Cancer
    TAT-PDHPS1 is a YAP inhibitor composed of the endogenous peptide PDHPS1 and the cell-penetrating peptide sequence TAT. PDHPS1 binds to protein phosphatase 2 phosphatase activator (PTPA), an essential activator of protein phosphatase 2A (PP2A), leading to increased YAP phosphorylation, which inactivates YAP and suppresses the expression of its downstream target genes. TAT-PDHPS1 is potentially useful in ovarian cancer research .
    TAT-PDHPS1
  • HY-P11074
    Sakacin P

    		Bacterial Infection
    Sakacin P is an antimicrobial peptide that targets Gram-positive bacteria (such as Listeria monocytogenes) and belongs to Class IIa bacteriocin. Sakacin P has almost no antimicrobial activity against Gram-negative bacteria. Sakacin P exerts its antimicrobial activity by interacting with bacterial cell membranes and destroying membrane integrity. Sakacin P can be used for the study of Listeria contamination and antimicrobial drugs in the food industry.
    Sakacin P
  • HY-P5917A
    Vm24-toxin TFA

    Vaejovis mexicanus peptide 24 TFA

    		 Potassium Channel Inflammation/Immunology Cancer
    Vm24-toxin (Vaejovis mexicanus peptide 24) TFA, a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin TFA shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin TFA folds into a distorted cystine-stabilized α/β motif consisting of a single-turn α-helix and a three-stranded antiparallel β-sheet, stabilized by four disulfide bridges. Vm24-toxin TFA attenuates the CD4 + effector memory T cell response to T cell receptor (TCR) stimulation .
    Vm24-toxin TFA
  • HY-160714
    Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH

    		ADC Linker Cancer
    Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH (Compound IM-3) is a cleavable ADC linker .
    Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH
  • HY-P3248
    J5 peptide

    Myelin basic protein (85-99) antagonist

    		 Biochemical Assay Reagents Inflammation/Immunology
    J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP85-99 to HLA-DR2. J5 peptide alleviates PLP139-151/MBP85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. J5 peptide can be used in research on inflammatory and immune diseases .
    J5 peptide
  • HY-P1576
    AMARA peptide

    		Salt-inducible Kinase (SIK) AMPK Inflammation/Immunology
    AMARA peptide is a substrate for SIK and AMPK.
    AMARA peptide
  • HY-P5708
    Adenoregulin

    Dermaseptin b2

    		 Antibiotic Fungal Bacterial Infection
    Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .
    Adenoregulin
  • HY-P4704
    α-Synuclein (61-95) (human)

    		α-synuclein Neurological Disease
    α-Synuclein (61-95) (human) is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .
    α-Synuclein (61-95) (human)
  • HY-147175
    Ala-Ala-Ala-NH-CH2OCH2COOH

    		ADC Linker Cancer
    Ala-Ala-Ala-NH-CH2OCH2COOH (Compound 37p) is a ADC linker, which serves as an intermediate for ADC synthesis .
    Ala-Ala-Ala-NH-CH2OCH2COOH
  • HY-P10546
    Polyalanine peptide

    pAla

    		 Bacterial Infection
    Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research .
    Polyalanine peptide
  • HY-P1100
    PM102

    HepArrest

    		 Thrombin Cardiovascular Disease
    PM102 (HepArrest) is a heparin antagonist that can reverses the anticoagulant effect of heparin. PM102 potently binds heparin (Kd = 36 nM) in vitro .
    PM102
  • HY-P5559
    ND1-YL2

    		PROTACs Cancer
    ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research .
    ND1-YL2
  • HY-P10562
    BMV Gag-(7−25)

    		TMV Others
    BMV Gag-(7 25) is an arginine-rich peptide with cell-penetrating ability. BMV Gag-(7 25) can be used in drug delivery and gene therapy research .
    BMV Gag-(7−25)
  • HY-P10796
    YARA peptide

    		MAPKAPK2 (MK2) Inflammation/Immunology
    YARA peptide, a cell-penetrating peptide, is a MK2 inhibitor. YARA-loaded nanoparticles decreases the levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in an ex vivo skin culture model. YARA peptide is promising for research of atopic dermatitis (AD) .
    YARA peptide
  • HY-P5588
    Dermaseptin-S4

    		Fungal Infection
    Dermaseptin-S4 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S4
  • HY-P5587
    Dermaseptin-S5

    		Fungal Infection
    Dermaseptin-S5 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S5
  • HY-P4977
    Tau Peptide (74-102) (Exon 3/Insert 2 Domain)

    		Tau Protein Neurological Disease
    Tau Peptide (74-102) (Exon 3/Insert 2 Domain) is aTau fragment.
    Tau Peptide (74-102) (Exon 3/Insert 2 Domain)
  • HY-P0263A
    Dermaseptin TFA

    		Bacterial Fungal Infection
    Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .
    Dermaseptin TFA
  • HY-P5593
    Dermaseptin-S2

    		Fungal Infection
    Dermaseptin-S2 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S2
  • HY-P2829
    Stresscopin (human)

    		CRFR Endocrinology
    Stresscopin (human) is a selective ligand of type 2 adrenocorticotropin-releasing hormone (CRH) receptors and can be used in the research of stress-related diseases .
    Stresscopin (human)
  • HY-P5917
    Vm24-toxin

    Vaejovis mexicanus peptide 24

    		 Potassium Channel Inflammation/Immunology Cancer
    Vm24-toxin (Vaejovis mexicanus peptide 24), a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin folds into a distorted cystine-stabilized α/β motif consisting of a single-turn α-helix and a three-stranded antiparallel β-sheet, stabilized by four disulfide bridges. Vm24-toxin attenuates the CD4 + effector memory T cell response to T cell receptor (TCR) stimulation .
    Vm24-toxin
  • HY-P11765
    RESA peptide

    		Adrenergic Receptor Others
    RESA peptide is a substrate peptide of β-adrenergic receptor kinase (βARK). RESA peptide serves as a substrate for βARK-mediated phosphorylation, and its N-terminal acidic residues enhance phosphorylation efficiency and substrate binding capacity .
    RESA peptide
  • HY-P11560
    YLLDLLPAAASHR

    		Biochemical Assay Reagents Others
    YLLDLLPAAASHR is a peptide from egg proteins. YLLDLLPAAASHR can be used as a marker peptide for the detection of egg allergens using UHPLC-MS/MS .
    YLLDLLPAAASHR
  • HY-P11533S
    VGDSSGTAAAH-(Lys-13C6,15N2) TFA

    		Isotope-Labeled Compounds Others
    VGDSSGTAAAH-(Lys- 13C6, 15N2) TFA is the 13C- and 15N-labeled VGDSSGTAAAH.
    VGDSSGTAAAH-(Lys-13C6,15N2) TFA
  • HY-P11630
    ZM-804

    		Bacterial Cardiovascular Disease Infection
    ZM-804 is a cationic α-helix antimicrobial peptide. ZM-804 targets bacterial cell membranes. ZM-804 demonstrates antimicrobial activity and prevents the infection of tomato plants by Pst DC3000. ZM-804 inhibits the growth of B. subtilis and E. coli (the same MICs of 41.10 μg/mL). ZM-804 exhibits low hemolytic activity .
    ZM-804

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