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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Alpha-Gal
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Alpha-Gal" in MCE Product Catalog:
2
Target:
Research Areas:
Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
Synonyms: 4MU-α-Gal
Target:
Research Areas:
4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA .
Target:
Research Areas:
X-alpha-Gal is a chromogenic substrate that is used to screen colonies with high activity of β-galactopyranoside. X-alpha-Gal also detects α-galactosidase activity. X-alpha-Gal can be used in yeast two hybrid screening for MEL1 gene activation. X-alpha-Gal can be used with Matchmaker GAL4-based products to confirm protein interactions .
Cat. No.: HY-P0232
CAS No.: 116783-35-8
Synonyms: Fmoc-Thr(Ac₃AcNH-α-Gal)-OH
Target:
Research Areas:
Synonyms: Fmoc-Ser-(GalNAc(Ac)3-Alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH
Research Areas:
Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH (Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH) is a protected glycosylated amino acid and Tn antigen. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH serves as a building block in the solid-phase synthesis of Tn-based cancer vaccine constructs. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH supports solid-phase peptide synthesis .
Cat. No.: HY-E70052
CAS No.: 128449-51-4
Synonyms: GGTA1
Target:
Research Areas:
alpha-1,3-Galactosyltransferase (a1,3GalT) (GGTA1) catalyzes the generation of the α-gal glycan via the transfer of a galactose (Gal) in α1-3 linkage, from a uridyl-diphosphate (UDP) donor onto the N-acetyllactosamine (Galβ1,4GlcNAc-R) of glycoproteins. alpha-1,3-Galactosyltransferase (a1,3GalT) is responsible for the synthesis of the α-galactose (α-Gal) epitope found in most mammalian species .
Cat. No.: HY-E70053
CAS No.: 37257-33-3
Synonyms: Alpha 1,3GT
Target:
Research Areas:
alpha-1,3-Galactosyltransferase (GTB) (alpha 1,3GT) catalyzes the synthesis of the xenoantigen or α-galactose (α-Gal) epitope. alpha-1,3-Galactosyltransferase (GTB) transfers galactose from UDP-Gal to type 1 or type 2, αFuc1→2βGal-R (H)-terminating acceptors .
Cat. No.: HY-158461
Synonyms: Galactose-Alpha-1,3-Galactose, 2-AA labelled
Cat. No.: HY-158462
Synonyms: Galactose-Alpha-1,3-Galactose, 2-AB labelled
Cat. No.: HY-14929
CAS No.: 108147-54-2
Synonyms: GR181413A free base; 1-DeoxyGalactonojirimycin
Target:
Research Areas:
Migalastat (GR181413A free base) is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
Cat. No.: HY-156996
CAS No.: 1821461-84-0
Target:
Research Areas:
AGI-134 is a fully synthetic alpha-Gal glycolipid. AGI-134 invokes CD8+ T cell-mediated immunity. AGI-134 induces tumor cell destruction and phagocytosis .
Cat. No.: HY-W728096
Synonyms: GR181413A-d5 free base
Cat. No.: HY-W740650
CAS No.: 1219134-37-8
Synonyms: GR181413A-15N
Cat. No.: HY-RS19435
Target:
Research Areas:
Ggta1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ggta1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E71724
Target:
Research Areas:
Bovine α-1,3-galactosyltransferase (recombinant) (EC 2.4.1.87) is a hexosyltransferase primarily responsible for adding α-D-galactose (α-Gal) to the termini of glycan chains, participating in the formation of the structures of glycoproteins, glycolipids, and blood group antigens.
Cat. No.: HY-14929S
Synonyms: GR181413A-d2
Cat. No.: HY-104004R
CAS No.: 120173-57-1
Synonyms: Fmoc-Ser-(GalNAc(Ac)3-Alpha-D)-OH (Standard); Fmoc-Ser[GalNAc(Ac)3-α-D]-OH (Standard); Fmoc-Ser(Ac3AcNH-α-Gal)-OH (Standard)
Research Areas:
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Standard) is the analytical standard of Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (HY-104004). This product is intended for research and analytical applications. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH (Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH) is a protected glycosylated amino acid and Tn antigen. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH serves as a building block in the solid-phase synthesis of Tn-based cancer vaccine constructs. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH supports solid-phase peptide synthesis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
