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  4. Fmoc-Thr[GalNAc(Ac)3-α-D]-OH

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH  (Synonyms: Fmoc-Thr(Ac?AcNH-α-Gal)-OH)

製品番号: HY-P0232 純度: 99.08%
COA 取扱説明書 Technical Support

AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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Fmoc-Thr[GalNAc(Ac)3-α-D]-OH

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 構造式

CAS 番号 : 116783-35-8

容量 価格（税別） 在庫状況 数量
5 mg $100 在庫あり
10 mg $165 在庫あり
25 mg $336 在庫あり
50 mg $576 在庫あり
100 mg $816 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 関連抗体

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製品説明

AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

体外実験

The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn +antigen). This precursor is generated in the Golgi apparatus on newly synthesized glycoproteins by a family of polypeptide α- N-acetylgalactosaminyltransferases (ppGalNAcTs) and then extended to the common core 1 O-glycan Galβ1-3GalNAcα1-OSer/Thr (T antigen) by a single enzyme termed the T-synthase (core 1 β3-galactosyltransferase or C1GalT). Formation of the active form of the T-synthase requires a unique molecular chaperone termed Cosmc, encoded by Cosmc on the X-chromosome[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 関連抗体
分子量

670.66

分子式

C33H38N2O13
CAS 番号
Appearance

Solid

Color

White to off-white

輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 116.67 mg/mL (173.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4911 mL 7.4553 mL 14.9107 mL
5 mM 0.2982 mL 1.4911 mL 2.9821 mL
10 mM 0.1491 mL 0.7455 mL 1.4911 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.08%

COA (259 KB) HNMR (337 KB) LCMS (101 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4911 mL 7.4553 mL 14.9107 mL 37.2767 mL
5 mM 0.2982 mL 1.4911 mL 2.9821 mL 7.4553 mL
10 mM 0.1491 mL 0.7455 mL 1.4911 mL 3.7277 mL
15 mM 0.0994 mL 0.4970 mL 0.9940 mL 2.4851 mL
20 mM 0.0746 mL 0.3728 mL 0.7455 mL 1.8638 mL
25 mM 0.0596 mL 0.2982 mL 0.5964 mL 1.4911 mL
30 mM 0.0497 mL 0.2485 mL 0.4970 mL 1.2426 mL
40 mM 0.0373 mL 0.1864 mL 0.3728 mL 0.9319 mL
50 mM 0.0298 mL 0.1491 mL 0.2982 mL 0.7455 mL
60 mM 0.0249 mL 0.1243 mL 0.2485 mL 0.6213 mL
80 mM 0.0186 mL 0.0932 mL 0.1864 mL 0.4660 mL
100 mM 0.0149 mL 0.0746 mL 0.1491 mL 0.3728 mL
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Fmoc-Thr[GalNAc(Ac)3-α-D]-OH Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

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製品名:
Fmoc-Thr[GalNAc(Ac)3-α-D]-OH
製品番号:
HY-P0232
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