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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
Bi-functional drug
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "Bi-functional drug" in MCE Product Catalog:
Cat. No.: HY-157763
Target:
Research Areas:
Mal-PEG1-Val-Cit-PABC-diphosphate-BTK degrader-1 is a cleavable linker-payload conjugate and cereblon-binding BTK bifunctional degrader. Mal-PEG1-Val-Cit-PABC-diphosphate-BTK degrader-1 induces BTK degradation and exerts cytotoxic effects when delivered via CD79b monoclonal antibody. Mal-PEG1-Val-Cit-PABC-diphosphate-BTK degrader-1, when formulated as a CD79b antibody-drug conjugate, achieves sustained in vivo BTK degradation in tumor-bearing mice with reduced systemic payload exposure. Mal-PEG1-Val-Cit-PABC-diphosphate-BTK degrader-1 can be used for the research of activated b-cell-like diffuse large b-cell lymphoma (ADC linker: (HY-130944); PROTAC: (HY-163295)) .
Cat. No.: HY-100133A
Purity: 96.18%
Cat. No.: HY-W011118
CAS No.: 23911-26-4
Research Areas:
DTPA anhydride is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. DTPA anhydride can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy.
Cat. No.: HY-155902C
CAS No.: 88504-24-9
Synonyms: Maleimide-PEG3400-Hydroxy
Cat. No.: HY-163363
CAS No.: 2779507-62-7
Target:
Research Areas:
β-AR antagonist 2 (compound 43) is an antagonist of β-AR (IC50: 0.17 μM). β-AR-IN-1 inhibits the growth of mouse A549 xenograft tumors and shows cardioprotective efficacy against DOX-induced HF in C57 mice .
Cat. No.: HY-136991
CAS No.: 95676-71-4
Target:
Research Areas:
Basacv is a DNA-polyintercalating bifunctional compound with DNA-high affinity. Basacv is structurally analogous to the antibiotic anti-tumour drug Triostin A and act as a bis-intercalator .
Cat. No.: HY-W1048552
Cat. No.: HY-W1049129B
Cat. No.: HY-W1049129C
Cat. No.: HY-122939
CAS No.: 161876-61-5
Research Areas:
MAIPGG is a bifunctional chelator and an intermediate in the synthesis of radionuclide drug conjugates (RDCs). MAIPGG can be for the radiolabeling of a variety of monoclonal antibodies with 99mTc or 186Re, which then can be used for radioimmunodetection and radioimmunotherapy of cancer .
Cat. No.: HY-W1048574E
Synonyms: OHC-PEG20000-carboxyl
Cat. No.: HY-W1048574I
Synonyms: OHC-PEG3400-carboxyl
Cat. No.: HY-155902D
CAS No.: 88504-24-9
Synonyms: Maleimide-PEG10000-Hydroxy
Cat. No.: HY-W1049129D
Cat. No.: HY-W1048574A
Synonyms: OHC-PEG2000-carboxyl
Cat. No.: HY-W1048574C
Synonyms: OHC-PEG5000-carboxyl
Cat. No.: HY-W1048574D
Synonyms: OHC-PEG10000-carboxyl
Cat. No.: HY-W1048574H
Synonyms: OHC-PEG1000-carboxyl
Cat. No.: HY-W1048574J
Synonyms: OHC-PEG40000-carboxyl
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
