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Results for "

Brompheniramine

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0480
    Brompheniramine maleate
    2 Publications Verification

    (±)-Brompheniramine maleate

    		 Histamine Receptor mAChR Potassium Channel Sodium Channel Calcium Channel Neurological Disease Inflammation/Immunology Endocrinology
    Brompheniramine ((±)-Brompheniramine) maleate is a potent and orally active antihistamine of the alkylamine class. Brompheniramine maleate is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine maleate can block the hERG channels, calcium channels, and sodium channels with IC50s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine maleate has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research .
    Brompheniramine maleate
  • HY-A0191
    Dexbrompheniramine

    (+)-Brompheniramine; (S)-Brompheniramine

    		 Endogenous Metabolite Histamine Receptor TRP Channel Neurological Disease Metabolic Disease Inflammation/Immunology
    Dexbrompheniramine ((+)-Brompheniramine; (S)-Brompheniramine) is a dual inhibitor of histamine H1 receptor and TRPV1 receptor that can cross the blood-brain barrier. Dexbrompheniramine exerts its effects by functionally blocking H1 receptor activity and dose-dependently inhibiting TRPV1-mediated calcium responses, including Capsaicin (HY-10448)-induced responses. The combination of Dexbrompheniramine with Cimetidine (HY-14289) eliminates histamine-induced and sham-feeding-induced drinking behavior, whereas Dexbrompheniramine alone does not induce thirst or alter sham-feeding behavior in rats. Dexbrompheniramine can be used in the research of chronic cough and related pathological mechanisms .
    Dexbrompheniramine
  • HY-B0480A
    Brompheniramine
    2 Publications Verification

    (±)-Brompheniramine

    		 Histamine Receptor mAChR Potassium Channel Sodium Channel Calcium Channel Neurological Disease Inflammation/Immunology Endocrinology
    Brompheniramine ((±)-Brompheniramine) is a potent and orally active antihistamine of the alkylamine class. Brompheniramine is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine can block the hERG channels, calcium channels, and sodium channels with IC50s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research .
    Brompheniramine
  • HY-402545
    (-)-Brompheniramine

    (R)-Brompheniramine

    		 Histamine Receptor Inflammation/Immunology
    (-)-Brompheniramine is a H1 receptor antagonist with antiallergic activity .
    (-)-Brompheniramine
  • HY-A0191A
    Dexbrompheniramine maleate

    (+)-Brompheniramine maleate; (S)-Brompheniramine maleate

    		 TRP Channel Histamine Receptor Inflammation/Immunology
    Dexbrompheniramine ((+)-Brompheniramine; (S)-Brompheniramine) maleate is a dual inhibitor of histamine H1 receptor and TRPV1 receptor that can cross the blood-brain barrier. Dexbrompheniramine maleate exerts its effects by functionally blocking H1 receptor activity and dose-dependently inhibiting TRPV1-mediated calcium responses, including Capsaicin (HY-10448)-induced responses. The combination of Dexbrompheniramine maleate with Cimetidine (HY-14289) eliminates histamine-induced and sham-feeding-induced drinking behavior, whereas Dexbrompheniramine maleate alone does not induce thirst or alter sham-feeding behavior in rats. Dexbrompheniramine maleate can be used in the research of chronic cough and related pathological mechanisms .
    Dexbrompheniramine maleate
  • HY-B0480AR
    Brompheniramine (Standard)

    (±)-Brompheniramine (Standard)

    		 Reference Standards Histamine Receptor mAChR Potassium Channel Sodium Channel Calcium Channel Neurological Disease Inflammation/Immunology Endocrinology
    Brompheniramine (Standard) is the analytical standard of Brompheniramine. This product is intended for research and analytical applications. Brompheniramine ((±)-Brompheniramine) is a potent and orally active antihistamine of the alkylamine class. Brompheniramine is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine can block the hERG channels, calcium channels, and sodium channels with IC50s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research [4].
    Brompheniramine (Standard)
  • HY-B0480R
    Brompheniramine maleate (Standard)

    (±)-Brompheniramine maleate (Standard)

    		 Reference Standards Histamine Receptor mAChR Potassium Channel Sodium Channel Calcium Channel Neurological Disease Inflammation/Immunology Endocrinology
    Brompheniramine (maleate) (Standard) is the analytical standard of Brompheniramine (maleate). This product is intended for research and analytical applications. Brompheniramine ((±)-Brompheniramine) maleate is a potent and orally active antihistamine of the alkylamine class. Brompheniramine maleate is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine maleate can block the hERG channels, calcium channels, and sodium channels with IC50s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine maleate has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research .
    Brompheniramine maleate (Standard)

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