4 Results for "

C1s Enzyme

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "C1s Enzyme" in MCE Product Catalog:

Cat. No.: HY-E70390
Synonyms: masp-2, c1 esterase, c1-esterase
Target:  

Wnt

C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity .
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Cat. No.: HY-P5278
CAS No.: 130698-88-3
Target:  

Ser/Thr Protease

Research Areas:  

Others

Z-Gly-Arg-Thiobenzyl ester is a synthetic peptide substrate used to detect the cleavage activity of C1r. Z-Gly-Arg-Thiobenzyl ester can be cleaved by proteases such as C1r, and when used in combination with DTNB (HY-15915) , it enables colorimetric determination of protease activity, which can be applied to enzymological studies related to the complement system .
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Cat. No.: HY-E70534
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C1s Proenzyme, the native form of C1s enzyme, is an inactive zymogen until C1 is activated. C1 complex binds to and is activated by antigen-antibody complexes (immune complexes) yielding C1r enzyme. C1r enzyme in the C1 complex activates C1s proenzyme generating C1s enzyme .
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Cat. No.: HY-P5528
Target:  

Peptides

Research Areas:  

Others

2Abz-SLGRKIQIK(Dnp)-NH2 is a biological active peptide. (This peptide is a second complement component (C2), the physiological substrate for the proenzyme Cls, first complement component. The complement system is a central component of host defense but can also contribute to the inflammation seen in pathological conditions. The C1s protease of the C1 complex initiates the host defense pathway. This peptide employs 2Abz/Dnp FRET pair for quantitation of complement enzyme activity.)
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