Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
CRX
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "CRX" in MCE Product Catalog:
Synonyms: CRX-601
Target:
Research Areas:
GSK1795091 (CRX-601), an immunologic stimulator, is a synthetic TLR4 agonist. Antitumor activity. GSK1795091 can be used as a vaccine adjuvant to enhance both mucosal and systemic immunity to influenza virus vaccines. Not only, GSK1795091 inhibits tumor growth and increases the survival in mice model, but results in long term survival in influenza challenge model in mice .
Cat. No.: HY-155801
CAS No.: 216014-14-1
Research Areas:
Cardiovascular Disease Infection Neurological Disease Inflammation/Immunology Cancer
CRX 527 is a TLR4 agonist. CRX 527 activates the MyD88-dependent, TRIF-dependent, and TRAF6/NF-κB signaling pathways downstream of TLR4, mimics lipid A, and regulates antigen processing and presentation by dendritic cells. CRX 527 stimulates innate immune responses and enhances vaccine efficacy. CRX 527 maintains the structural integrity of hematopoietic tissues, spleen and intestine, alleviates radiation-induced damage, preserves intestinal homeostasis, and inhibits apoptosis, inflammatory responses, oxidative stress and DNA damage. CRX 527 can be used in the research of acute radiation syndrome, melanoma, HPV-related tumors and intracerebral hemorrhage .
Cat. No.: HY-118984
CAS No.: 245515-64-4
Target:
Research Areas:
CRX-526 is a TLR4 antagonist that can block the interaction of lipopolysaccharide (LPS, HY-D1056) with the immune system, including preventing the expression of pro-inflammatory genes stimulated by LPS, as well as blocking the release of TNF-α induced by LPS. CRX-526 exhibits anti-inflammatory effects in two mouse models of colitis (namely, the dextran sodium sulfate-induced colitis model and the multidrug resistance gene 1a-deficient mouse model) .
Target:
Research Areas:
CRX000227 is a PPAR modulator. CRX000227 can be used for research of metabolic or cell proliferative disorders .
Cat. No.: HY-RS03203
Target:
Research Areas:
CRX Human Pre-designed siRNA Set A contains three designed siRNAs for CRX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991978
Synonyms: CRX01
Target:
Research Areas:
Cat. No.: HY-P86825
Synonyms: Cone rod homeobox antibody; Cone rod homeobox protein antibody; Cone rod homeobox-containing gene antibody; cone-rod homeobox antibody; Cone-rod homeobox protein antibody; CORD 2 antibody; CRD antibody; CRX antibody; CRX_HUMAN antibody; LCA 7 antibody; Cone rod homeobox antibody; Cone rod homeobox protein antibody; Cone rod homeobox-containing gene antibody; cone-rod homeobox antibody; Cone-rod homeobox protein antibody; CORD 2 antibody; CRD antibody; CRX antibody; CRX_HUMAN antibody; LCA 7 antibody; LCA7 antibody; Orthodenticle homeobox 3 antibody; OTX 3 antibody; OTX3 antibody;
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
