1233589-81-5

GSK1795091 Chemical Structure
1233589-81-5

Chemical Structure

GSK1795091

Synonym(s): CRX-601

  • CAS No.: 1233589-81-5
  • Formula:C81H157N2O16P
  • Molecular Weight:1446.09

IUPAC Name: O-((2R,3R,4R,5S,6R)-3-((R)-3-(decyloxy)tetradecanamido)-4-(((R)-3-(decyloxy)tetradecanoyl)oxy)-6-(hydroxymethyl)-5-(phosphonooxy)tetrahydro-2H-pyran-2-yl)-N-((R)-3-(decyloxy)tetradecanoyl)-L-serine

InChIKey: ICLAYQQKWJGHBV-XJZMHMBSSA-N

SMILES: O=C(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)O[C@@H]([C@@H]([C@H]1CO)O[P](O)(O)=O)[C@H]([C@@H](O1)OC[C@@H](C(O)=O)NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O

Biological Activity: GSK1795091 (CRX-601), an immunologic stimulator, is a synthetic TLR4 agonist. Antitumor activity. GSK1795091 can be used as a vaccine adjuvant to enhance both mucosal and systemic immunity to influenza virus vaccines. Not only, GSK1795091 inhibits tumor growth and increases the survival in mice model, but results in long term survival in influenza challenge model in mice[1][2][3].

Cat. No. Product Name Purity Description Pricing
HY-111792 		GSK1795091 94.48% GSK1795091 (CRX-601), an immunologic stimulator, is a synthetic TLR4 agonist. Antitumor activity. GSK1795091 can be used as a vaccine adjuvant to enhance both mucosal and systemic immunity to influenza virus vaccines. Not only, GSK1795091 inhibits tumor growth and increases the survival in mice model, but results in long term survival in influenza challenge model in mice.
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