CRX-526
CRX-526 is a TLR4 antagonist that can block the interaction of lipopolysaccharide (LPS, HY-D1056) with the immune system, including preventing the expression of pro-inflammatory genes stimulated by LPS, as well as blocking the release of TNF-α induced by LPS. CRX-526 exhibits anti-inflammatory effects in two mouse models of colitis (namely, the dextran sodium sulfate-induced colitis model and the multidrug resistance gene 1a-deficient mouse model).
For research use only. We do not sell to patients.
- CAS No.: 245515-64-4
- Formula: C69H127N2O19P
- Molecular Weight:1319.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 245515-64-4
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Molecular Weight 1319.72
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Formula C69H127N2O19P
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SMILES
O=C([C@H](CO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1NC(C[C@@H](CCCCCCCCCCC)OC(CCCCC)=O)=O)OC(C[C@@H](CCCCCCCCCCC)OC(CCCCC)=O)=O)OP(O)(O)=O)CO)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCC)=O)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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