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Cat. No.: HY-P87964

CRX Antibody (YA7649)

CRX Antibody (YA7649) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CRX.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	IHC-F IHC-F: Immunohistochemistry-Frozen	IF-Tissue IF-Tissue: Immunofluorescence-Tissue
Dilution Ratio	1:500-2000	1:100-200	1:100-200	1:100-200

Description

CRX Antibody (YA7649) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CRX.

Host Rabbit
Clonality Recombinant
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 37 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 32 kDa

Immunogen

A synthesized peptide derived from human Cone rod homeobox protein

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

CRX transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors
Subcellular Localization

Nucleus
Expression

Tissue_Specificity: Retina
Isoforms & Post-Translational Modification

O43186: 299 amino acids, molecular weight 32261 Da.
Subunit

Interacts (via the homeobox) with NRL (via the leucine-zipper domain)
SwissProt ID

O43186