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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
Cath-L-dBET1
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "Cath-L-dBET1" in MCE Product Catalog:
Cat. No.: HY-173257
Target:
Research Areas:
Cath-L-dBET1 is a PROTAC degrader targeting BRD4. Cath-L-dBET1 has an IC50 value of 2.8 μM in MDA-MB-231 cells. Cath-L-dBET1 can be activated by cathepsin L (Cath-L) and recruit the E3 ubiquitin ligase and degrade BRD4 through ubiquitin-proteasome system. Hyp-dBET1 can be used for anti-tumor study [1].
Cat. No.: HY-178092
Target:
Research Areas:
Boc-(S)-Lys(Ac)-NH(4-CHO-Ph) is a PROTAC linker. Boc-(S)-Lys(Ac)-NH(4-CHO-Ph) can be used to synthesize the PROTAC Cath-L-dBET1 (HY-173257).
Cat. No.: HY-178094
CAS No.: 1101702-81-1
Target:
Ligands for Target Protein for PROTAC Target Protein Ligand-Linker Conjugates Epigenetic Reader Domain
Research Areas:
BRD4 ligand 13 is a BRD4 ligand that can be used for the synthesis of PROTACs, such as Cath-L-dBET1 (HY-173257). BRD4 ligand 13 is a target protein ligand-conjugate that can be used for the synthesis of PROTACs, such as SJH1-51B (HY-162240) [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
