12 Results for "

Cimetidine

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "Cimetidine" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-14289
CAS No.: 51481-61-9
Purity:  ≥98.0%
Synonyms: SKF-92334
Cimetidine (SKF-92334) is an orally active, inverse and BBB-permeable histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine has anti-cancer and anti-inflammatory activity .
loading...
    loading...
Cat. No.: HY-A0191
CAS No.: 132-21-8
Synonyms: (+)-Brompheniramine; (S)-Brompheniramine
Dexbrompheniramine ((+)-Brompheniramine; (S)-Brompheniramine) is a dual inhibitor of histamine H1 receptor and TRPV1 receptor that can cross the blood-brain barrier. Dexbrompheniramine exerts its effects by functionally blocking H1 receptor activity and dose-dependently inhibiting TRPV1-mediated calcium responses, including Capsaicin (HY-10448)-induced responses. The combination of Dexbrompheniramine with Cimetidine (HY-14289) eliminates histamine-induced and sham-feeding-induced drinking behavior, whereas Dexbrompheniramine alone does not induce thirst or alter sham-feeding behavior in rats. Dexbrompheniramine can be used in the research of chronic cough and related pathological mechanisms .
loading...
    loading...
Cat. No.: HY-14289R
CAS No.: 51481-61-9
Synonyms: SKF-92334 (Standard)
Cimetidine (Standard) is the analytical standard of Cimetidine. This product is intended for research and analytical applications. Cimetidine (SKF-92334) is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine has anti-cancer and anti-inflammatory activity .
loading...
    loading...
Cat. No.: HY-B1109R
CAS No.: 32795-44-1
Synonyms: Acecainide (Standard); NAPA (Standard)
Cimetidine (hydrochloride) (Standard) is the analytical standard of Cimetidine (hydrochloride). This product is intended for research and analytical applications. Cimetidine (SKF-92334) hydrochloride is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine hydrochloride is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine hydrochloride has anti-cancer and anti-inflammatory activity .
loading...
    loading...
Cat. No.: HY-136338
CAS No.: 54237-72-8
Purity:  ≥97.0%
Synonyms: Cimetidine sulphoxide
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment .
loading...
    loading...
Cat. No.: HY-136338R
CAS No.: 54237-72-8
Synonyms: Cimetidine sulphoxide (Standard)
Cimetidine sulfoxide (Standard) is the analytical standard of Cimetidine sulfoxide. This product is intended for research and analytical applications. Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment .
loading...
    loading...
Cat. No.: HY-14289AR
CAS No.: 70059-30-2
Synonyms: SKF-92334 hydrochloride (Standard)
Cimetidine (hydrochloride) (Standard) is the analytical standard of Cimetidine (hydrochloride). This product is intended for research and analytical applications. Cimetidine (SKF-92334) hydrochloride is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine hydrochloride is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine hydrochloride has anti-cancer and anti-inflammatory activity .
loading...
    loading...
Cat. No.: HY-14289A
CAS No.: 70059-30-2
Synonyms: SKF-92334 hydrochloride
Research Areas:  

Metabolic Disease Cancer

Cimetidine (SKF-92334) hydrochloride is an orally active, inverse and BBB-permeable histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine hydrochloride is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine hydrochloride has anti-cancer and anti-inflammatory activity .
loading...
    loading...
Cat. No.: HY-14289S
CAS No.: 1185237-29-9
Synonyms: SKF-92334-d3
Cimetidine-d3 is the deuterium labeled Cimetidine. Cimetidine (SKF-92334) is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine is an inverse agonist. Cimetidine has anti-cancer and anti-inflammatory activity .
loading...
    loading...
Cat. No.: HY-A0191A
CAS No.: 2391-03-9
Synonyms: (+)-Brompheniramine maleate; (S)-Brompheniramine maleate
Research Areas:  

Inflammation/Immunology

Dexbrompheniramine ((+)-Brompheniramine; (S)-Brompheniramine) maleate is a dual inhibitor of histamine H1 receptor and TRPV1 receptor that can cross the blood-brain barrier. Dexbrompheniramine maleate exerts its effects by functionally blocking H1 receptor activity and dose-dependently inhibiting TRPV1-mediated calcium responses, including Capsaicin (HY-10448)-induced responses. The combination of Dexbrompheniramine maleate with Cimetidine (HY-14289) eliminates histamine-induced and sham-feeding-induced drinking behavior, whereas Dexbrompheniramine maleate alone does not induce thirst or alter sham-feeding behavior in rats. Dexbrompheniramine maleate can be used in the research of chronic cough and related pathological mechanisms .
loading...
    loading...
Cat. No.: HY-W151280
CAS No.: 31857-31-5
Target:  

Drug Intermediate

Research Areas:  

Others

2-Cyano-1,3-dimethylguanidine is a Cimetidine (HY-14289) impurity.
loading...
    loading...
Cat. No.: HY-136818
CAS No.: 95833-19-5
Target:  

Histamine Receptor

Research Areas:  

Endocrinology

DA 4643 (hydrochloride) is an H2 receptor antagonist with the chemical name 2-guanidino-4 (3-methylaminomethyleneiminophenyl) thiazole dihydrochloride. It has a weak interaction with cytochrome P-450 and has a less inhibitory effect on P-450 than cimetidine and tiotidine. DA 4643 (hydrochloride) is able to inhibit both enzymatic and non-enzymatic lipid peroxidation reactions. This inhibition may not be achieved by inhibiting agent metabolizing enzymes, but rather due to the antioxidant properties of the compound itself. Compared with other H2 receptor antagonists such as cimetidine, ranitidine and tiotidine, DA 4643 (hydrochloride) shows a unique effect in lipid peroxidation inhibition. These properties make DA 4643 (hydrochloride) a potential H2 receptor antagonist with multiple mechanisms of action.
loading...
    loading...
  • 1