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Cinchona

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By Targets:	Acyltransferase (1) Apoptosis (3) Autophagy (2) Bacterial (2) Calcium Channel (2) Caspase (2) Dengue Virus (9) Flavivirus (9) Isotope-Labeled Compounds (1) Parasite (17) Potassium Channel (10) Protein Arginine Deiminase (2) Reactive Oxygen Species (ROS) (2) Reference Standards (8) Serotonin Transporter (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (3) Infection (12) Inflammation/Immunology (4) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0143

Quinine Maximum Cited Publications 7 Publications Verification	Flavivirus Dengue Virus Parasite Potassium Channel	Infection
Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-N0173

Cinchonidine α-Quinidine	Serotonin Transporter Parasite	Infection
Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with K_is of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities .

HY-N7354

Quininic acid	Others	Cardiovascular Disease
Quininic acid, purified from Eucalyptus globulus, cinchona bark, and other plant products, is the most abundant organic acid .

HY-42034

Hydroquinine Dihydroquinine	Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase	Infection
Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .

HY-Y0152

Cinchonine 5 Publications Verification (8R,9S)-Cinchonine; LA40221	Apoptosis Parasite Autophagy Caspase Calcium Channel	Others Inflammation/Immunology Cancer
Cinchonine is a natural compound present in Cinchona bark with antimalarial, antitumor, anti-inflammatory, anti platelet-aggregation and anti-obesity properties. Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells .

HY-W010668

Quinine sulfate hydrate Maximum Cited Publications 7 Publications Verification	Flavivirus Dengue Virus Parasite Potassium Channel	Others
Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-D0143B

Quinine hemisulfate hydrate Maximum Cited Publications 7 Publications Verification	Parasite Potassium Channel	Infection
Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV, with an IC₅₀ of 169 μM .

HY-110082

Quinine (hydrochloride) Maximum Cited Publications 7 Publications Verification	Flavivirus Dengue Virus Parasite Potassium Channel	Cardiovascular Disease Infection Cancer
Quinine hydrochloride is an alkaloid extracted from cinchona bark and exhibits oral activity, acting as a potassium channel inhibitor. Quinine hydrochloride modulates the tolerance of red blood cells and presents dose-dependent toxicity and embryonic effects. Quinine hydrochloride is a typical hemolysin that directly lyses red blood cells, with cellular components of red blood cell membranes as its action targets. Quinine hydrochloride disrupts red blood cell membranes and induces hemolysis at high concentrations, while merely weakening the anti-hemolytic capacity of red blood cells at low concentrations. Quinine hydrochloride continuously reduces red blood cell tolerance after in vivo administration, and high doses can also alter blood cell counts. Quinine hydrochloride can be applied to researches related to red blood cell hemolysis, cancer and malaria .

HY-D0143A

Quinine dihydrochloride	Flavivirus Dengue Virus Parasite Potassium Channel	Infection
Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-N0173R

Cinchonidine (Standard) α-Quinidine (Standard)	Reference Standards Serotonin Transporter Parasite	Infection
Cinchonidine (Standard) is the analytical standard of Cinchonidine. This product is intended for research and analytical applications. Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities .

HY-B0433B

Quinine hemisulfate	Flavivirus Dengue Virus Parasite Potassium Channel	Infection
Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-W011241

Cinchonine hydrochloride (8R,9S)-Cinchonine hydrochloride; LA40221 hydrochloride	Apoptosis Parasite	Cancer
Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural alkaloid present in Cinchona bark, with antimalarial activity. Cinchonine hydrochloride activates endoplasmic reticulum (ER) stress-induced apoptosis in human liver cancer cells .

HY-D0143R

Quinine (Standard)	Dengue Virus Flavivirus Reference Standards Parasite Potassium Channel	Infection
Quinine (Standard) is the analytical standard of Quinine. This product is intended for research and analytical applications. Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-Y0152R

Cinchonine (Standard) (8R,9S)-Cinchonine (Standard); LA40221 (Standard)	Reference Standards Apoptosis Parasite Autophagy Caspase Calcium Channel	Others Inflammation/Immunology Cancer
Cinchonine (Standard) is the analytical standard of Cinchonine. This product is intended for research and analytical applications. Cinchonine is a natural compound present in Cinchona bark with antimalarial, antitumor, anti-inflammatory, anti platelet-aggregation and anti-obesity properties. Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells .

HY-W010668R

Quinine sulfate hydrate (Standard)	Flavivirus Dengue Virus Reference Standards Parasite Potassium Channel	Others
Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .

HY-42034R

Hydroquinine (Standard) Dihydroquinine (Standard)	Reference Standards Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase	Inflammation/Immunology
Hydroquinine (Standard) is the analytical standard of Hydroquinine. Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .

HY-N19054

Cinchona ledgeriana extract	Others	Infection Neurological Disease Inflammation/Immunology
Cinchona ledgeriana extract, derived from the bark of the cinchona tree, is rich in alkaloids such as quinine and quinidine, and has antimalarial, anti-inflammatory, analgesic, and antioxidant effects.

HY-W740048

Quinine-d3	Isotope-Labeled Compounds Potassium Channel Parasite Flavivirus Dengue Virus	Infection
Quinine-d₃ is the deuterium labeled Quinine (HY-D0143). Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC₅₀ of 169 μM .

HY-D0143AR

Quinine dihydrochloride (Standard)	Flavivirus Dengue Virus Reference Standards Parasite Potassium Channel	Infection
Quinine (dihydrochloride) (Standard) is the analytical standard of Quinine (dihydrochloride). This product is intended for research and analytical applications. Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .

HY-117651R

2-Fluoropalmitic acid (Standard)	Reference Standards Acyltransferase	Cancer
Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .

HY-N10833

2-Hydroxy-1,3,4-trimethoxyanthraquinone	Others	Others
2-Hydroxy-1,3,4-trimethoxyanthraquinone is a anthraquinone that can be found in Cinchona ledgeriana .

HY-N7354R

Quininic acid (Standard)	Others Reference Standards	Cardiovascular Disease
Quininic acid (Standard) is the analytical standard of Quininic acid (HY-N7354). This product is intended for research and analytical applications. Quininic acid, purified from Eucalyptus globulus, cinchona bark, and other plant products, is the most abundant organic acid .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0143

Quinine Maximum Cited Publications 7 Publications Verification	Cinchona succirubra Pav. ex Klotzsch Infection Alkaloids Classification of Application Fields Rubiaceae Quinoline Alkaloids Plants Disease Research Fields Source Classification	Flavivirus Dengue Virus Parasite Potassium Channel
Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-N0173

Cinchonidine α-Quinidine	Infection Alkaloids Piperidine Alkaloids Structural Classification Cinchona officinalis Linn. Classification of Application Fields Rubiaceae Quinoline Alkaloids Plants Disease Research Fields	Serotonin Transporter Parasite
Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with K_is of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities .

HY-N7354

Quininic acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Rubiaceae Cinchona calisaya Wedd. Plants Disease Research Fields Source Classification	Others
Quininic acid, purified from Eucalyptus globulus, cinchona bark, and other plant products, is the most abundant organic acid .

HY-42034

Hydroquinine Dihydroquinine	Alkaloids Classification of Application Fields Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase
Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .

HY-Y0152

Cinchonine 5 Publications Verification (8R,9S)-Cinchonine; LA40221	Alkaloids Piperidine Alkaloids Classification of Application Fields Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Disease Research Fields Source Classification Cancer	Apoptosis Parasite Autophagy Caspase Calcium Channel
Cinchonine is a natural compound present in Cinchona bark with antimalarial, antitumor, anti-inflammatory, anti platelet-aggregation and anti-obesity properties. Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells .

HY-W010668

Quinine sulfate hydrate Maximum Cited Publications 7 Publications Verification	Plants Source Classification	Flavivirus Dengue Virus Parasite Potassium Channel
Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-D0143B

Quinine hemisulfate hydrate Maximum Cited Publications 7 Publications Verification	Infection Alkaloids Classification of Application Fields Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Disease Research Fields Source Classification	Parasite Potassium Channel
Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV, with an IC₅₀ of 169 μM .

HY-D0143A

Quinine dihydrochloride	Cinchona succirubra Pav. ex Klotzsch Structural Classification Alkaloids Piperidine Alkaloids Rubiaceae Plants Isoquinoline Alkaloids Source Classification	Flavivirus Dengue Virus Parasite Potassium Channel
Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-N0173R

Cinchonidine (Standard) α-Quinidine (Standard)	Alkaloids Piperidine Alkaloids Structural Classification Cinchona officinalis Linn. Rubiaceae Quinoline Alkaloids Plants	Reference Standards Serotonin Transporter Parasite
Cinchonidine (Standard) is the analytical standard of Cinchonidine. This product is intended for research and analytical applications. Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities .

HY-B0433B

Quinine hemisulfate	Cinchona succirubra Pav. ex Klotzsch Rubiaceae Quinoline Alkaloids Plants Source Classification	Flavivirus Dengue Virus Parasite Potassium Channel
Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-W011241

Cinchonine hydrochloride (8R,9S)-Cinchonine hydrochloride; LA40221 hydrochloride	Alkaloids other families Classification of Application Fields Quinoline Alkaloids Plants Disease Research Fields Cancer Source Classification	Apoptosis Parasite
Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural alkaloid present in Cinchona bark, with antimalarial activity. Cinchonine hydrochloride activates endoplasmic reticulum (ER) stress-induced apoptosis in human liver cancer cells .

HY-D0143R

Quinine (Standard)	Cinchona succirubra Pav. ex Klotzsch Alkaloids Structural Classification Rubiaceae Quinoline Alkaloids Plants Source Classification	Dengue Virus Flavivirus Reference Standards Parasite Potassium Channel
Quinine (Standard) is the analytical standard of Quinine. This product is intended for research and analytical applications. Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-Y0152R

Cinchonine (Standard) (8R,9S)-Cinchonine (Standard); LA40221 (Standard)	Alkaloids Piperidine Alkaloids Structural Classification Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Source Classification	Reference Standards Apoptosis Parasite Autophagy Caspase Calcium Channel
Cinchonine (Standard) is the analytical standard of Cinchonine. This product is intended for research and analytical applications. Cinchonine is a natural compound present in Cinchona bark with antimalarial, antitumor, anti-inflammatory, anti platelet-aggregation and anti-obesity properties. Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells .

HY-W010668R

Quinine sulfate hydrate (Standard)	Plants Source Classification	Flavivirus Dengue Virus Reference Standards Parasite Potassium Channel
Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .

HY-42034R

Hydroquinine (Standard) Dihydroquinine (Standard)	Alkaloids Structural Classification Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Source Classification	Reference Standards Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase
Hydroquinine (Standard) is the analytical standard of Hydroquinine. Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .

HY-N19054

Cinchona ledgeriana extract	Structural Classification Extract	Others
Cinchona ledgeriana extract, derived from the bark of the cinchona tree, is rich in alkaloids such as quinine and quinidine, and has antimalarial, anti-inflammatory, analgesic, and antioxidant effects.

HY-D0143AR

Quinine dihydrochloride (Standard)	Cinchona succirubra Pav. ex Klotzsch Natural Products Rubiaceae Plants Source Classification	Flavivirus Dengue Virus Reference Standards Parasite Potassium Channel
Quinine (dihydrochloride) (Standard) is the analytical standard of Quinine (dihydrochloride). This product is intended for research and analytical applications. Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .

HY-N10833

2-Hydroxy-1,3,4-trimethoxyanthraquinone	Quinones Anthraquinones Rubiaceae Cinchona calisaya Wedd. Plants Source Classification	Others
2-Hydroxy-1,3,4-trimethoxyanthraquinone is a anthraquinone that can be found in Cinchona ledgeriana .

HY-N7354R

Quininic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Rubiaceae Cinchona calisaya Wedd. Plants Source Classification	Others Reference Standards
Quininic acid (Standard) is the analytical standard of Quininic acid (HY-N7354). This product is intended for research and analytical applications. Quininic acid, purified from Eucalyptus globulus, cinchona bark, and other plant products, is the most abundant organic acid .

Cat. No.	Product Name	Chemical Structure

HY-W740048

Quinine-d3
Quinine-d₃ is the deuterium labeled Quinine (HY-D0143). Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC₅₀ of 169 μM .

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Cinchona

Inhibitors & Agonists

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Isotope-Labeled Compounds

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