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Quinine hemisulfate

7 Cited Publications
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Based on 7 publication(s) in Google Scholar

Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.

For research use only. We do not sell to patients.

  • CAS No.: 804-63-7
  • Formula: C20H24N2O2.1/2H2SO4
  • Molecular Weight:373.45
  • Storage:

    4°C, protect from light, stored under nitrogen

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

  • Quinine hemisulfate Chemical Structure
    Quinine hemisulfate Chemical Structure
  • Experimental Validation Results for Quinine hemisulfate
  • Experimental Validation Results for Quinine hemisulfate
  • Experimental Validation Results for Quinine hemisulfate
  • Experimental Validation Results for Quinine hemisulfate
  • Experimental Validation Results for Quinine hemisulfate
CAS No.: 804-63-7
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  • Quinine hemisulfate Chemical Structure
    Quinine hemisulfate Chemical Structure
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  • 1/16

    Quinine hemisulfate purchased from MedChemExpress. Usage Cited in: Neurosci Bull. 2025 May 6. [Abstract]

    Customer Validation
     Quinine (qui; 10 μM; 5 min) decreased the travel distance upon sound stimulation in zebrafish.

  • 1/16

    Quinine hemisulfate purchased from MedChemExpress. Usage Cited in: Neurosci Bull. 2025 May 6. [Abstract]

    Customer Validation
     Quinine (qui; 10 μM; 5 min) remained unchanged in the number of HCs in zebrafish.

  • 1/16

    Quinine hemisulfate purchased from MedChemExpress. Usage Cited in: Cell Mol Life Sci. 2025 Nov 25;82(1):419. [Abstract]

    Customer Validation
     Quinine (0-320 μM) showed no cytotoxicity for Primary pancreatic β cells.

  • 1/16

    Quinine hemisulfate purchased from MedChemExpress. Usage Cited in: J Mol Cell Biol. 2025 May 22;16(11):mjae051. [Abstract]

    Customer Validation
     Quinine (0-320 μM; 24 h) showed cytotoxicity in primary pancreatic β cells and HEK293T cells.

  • 1/16

    Quinine hemisulfate purchased from MedChemExpress. Usage Cited in: J Mol Cell Biol. 2025 May 22;16(11):mjae051. [Abstract]

    Customer Validation
     Quinine (0-40 μM) potentiated high glucose (25 mM)-evoked insulin secretion in a dose-dependent manner at 5–100 μM. However, under low-glucose (2 mM) conditions, quinine induced insulin secretion only at concentrations of 50–100 μM; without the addition of glucose, 5 μM quinine alone was not sufficient to stimulate insulin secretion.

  • Quinine hemisulfate