1. Anti-infection
    Membrane Transporter/Ion Channel
  2. Parasite
    Potassium Channel
  3. Quinine hemisulfate hydrate

Quinine hemisulfate hydrate 

Cat. No.: HY-D0143B
Handling Instructions

Quinine hemisulfate hydrate is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.

For research use only. We do not sell to patients.

Quinine hemisulfate hydrate Chemical Structure

Quinine hemisulfate hydrate Chemical Structure

CAS No. : 207671-44-1

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Description

Quinine hemisulfate hydrate is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM[1][2].

IC50 & Target

IC50: Parasite[1], 169 μM (mSlo3)[2]

Molecular Weight

391.48

Formula

C₂₀H₂₄N₂O₂.₁/₂H₂O₄S.H₂O

CAS No.

207671-44-1

SMILES

[H][[email protected]@]1([[email protected]](O)C2=CC=NC3=C2C=C(OC)C=C3)C[[email protected]]4[[email protected]@H](C=C)C[[email protected]@]1CC4.OS(O)(=O)=O.O.[1/2]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Quinine hemisulfateParasitePotassium ChannelKcsAanti-malariaparasitepotassiumchannelKCa5.1Slo3Inhibitorinhibitorinhibit

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Quinine hemisulfate hydrate
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HY-D0143B
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