2. Anti-infection Membrane Transporter/Ion Channel
  3. Parasite Potassium Channel
  4. Quinine hemisulfate hydrate

Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV, with an IC50 of 169 μM.

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Quinine hemisulfate hydrate Chemical Structure

Quinine hemisulfate hydrate Chemical Structure

CAS No. : 207671-44-1

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Other Forms of Quinine hemisulfate hydrate:

Quinine hemisulfate hydrate Related Antibodies

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Description

Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV, with an IC50 of 169 μM[1][2].

IC50 & Target

IC50: Parasite[1], 169 μM (mSlo3)[2]
Clinical Trial
Molecular Weight

391.48

Formula

C20H24N2O2.1/2H2O4S.H2O
CAS No.
SMILES

[H][C@@]1([C@H](O)C2=CC=NC3=C2C=C(OC)C=C3)C[C@H]4[C@@H](C=C)C[N@@]1CC4.OS(O)(=O)=O.O.[1/2]
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Quinine hemisulfate hydrate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Quinine hemisulfate207671-44-1ParasitePotassium ChannelKcsAanti-malariaparasitepotassiumchannelKCa5.1Slo3Inhibitorinhibitorinhibit

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