Cinchonine hydrochloride
Based on 5 publication(s) in Google Scholar
Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural alkaloid present in Cinchona bark, with antimalarial activity. Cinchonine hydrochloride activates endoplasmic reticulum (ER) stress-induced apoptosis in human liver cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 5949-11-1
- Formula: C19H23ClN2O
- Molecular Weight:330.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Cinchonine hydrochloride
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Biological Activity
Chemical Information
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CAS No. 5949-11-1
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Molecular Weight 330.85
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Formula C19H23ClN2O
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SMILES
[H]Cl.O[C@@H](C1=CC=NC2=CC=CC=C12)[C@]3([H])[N@@]4C[C@H](C=C)[C@@H](CC4)C3
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Synonyms
(8R,9S)-Cinchonine hydrochloride; LA40221 hydrochloride
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
The interaction of cinchonine and immunoglobulin G and the development of a nanocomplex with improved anti-breast cancer activity. [Abstract]2025 Jan:287:138152. PMID: 39613056 -
Diabetes Obes Metab
AdipoRon attenuates steatosis, inflammation and fibrosis in murine diet-induced NASH via inhibiting ER stress. [Abstract]2025 Jun 17. PMID: 40528684 -
Respir Res
Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis. [Abstract]2024 Nov 9;25(1):401. PMID: 39522031 -
Front Cell Infect Microbiol
Inhibition of Porcine Epidemic Diarrhea Virus by Cinchonine via Inducing Cellular Autophagy. [Abstract]2022 Jun 14:12:856711. PMID: 35774410 -
Biomed Pharmacother
Cinchonine exerts anti-tumor and immunotherapy sensitizing effects in lung cancer by impairing autophagic-lysosomal degradation. [Abstract]2023 Aug:164:114980. PMID: 37301135
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cinchonine hydrochloride Related Classifications
HY-W011241 Related Classifications
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