4 Results for "

Cytochalasin G

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Cytochalasin G" in MCE Product Catalog:

Cytochalasin G
Cytochalasin G
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Cat. No.: HY-N14568
CAS No.: 54874-57-6
Category:  

Natural Products Microorganisms

Target:  

Arp2/3 Complex

Cytochalasin G has many biological activities, such as inhibiting cytoKinesis reversibly, inhibiting megasophil endocytosis and exocytosis .
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100
Cytochalasin D
Cytochalasin D
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100 Cited Publications
Cat. No.: HY-N6682
CAS No.: 22144-77-0
Synonyms: Zygosporin A; NSC 209835
Category:  

Infection Natural Products Microorganisms Disease Research Fields

Target:  

Exosomes Arp2/3 Complex Antibiotic YAP

Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap .
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Phallacidin
Phallacidin
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Cat. No.: HY-P2031
CAS No.: 26645-35-2
Category:  

Microorganisms Ketones, Aldehydes, Acids Other Diseases Disease Research Fields

Target:  

Arp2/3 Complex

Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a Kd of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .
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PSMA-HK9
PSMA-HK9
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Cat. No.: HY-P11893
Target:  

PSMA

Research Areas:  

Cancer

PSMA-HK9 is a ligand targeting prostate-specific membrane antigen (PSMA) that binds to PSMA with high affinity, with a Kd value of 4.76 nM. PSMA-HK9 can be labeled with the diagnostic radionuclide 68Ga for imaging applications, and this labeled conjugate exhibits high tumor uptake and low normal tissue uptake in vivo. PSMA-HK9 can be labeled with the radionuclide 177Lu for targeted radionuclide studies, and this labeled conjugate possesses efficient cellular endocytosis and tumor inhibitory activity. PSMA-HK9 can be used in studies related to prostate cancer .
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