9 Results for "

DAB452

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "DAB452" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-A0248A
CAS No.: 4135-11-9
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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Cat. No.: HY-W966282
CAS No.: 189681-70-7
Synonyms: DAB-452
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Aplindore (DAB-452) is a potent agonist of the dopamine D2 receptor, with the pKi of 9.1. Aplindore plays an important role in Parkinson's disease research .
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Cat. No.: HY-129507
CAS No.: 189681-71-8
Synonyms: DAB-452 fumarate
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Aplindore fumarate (DAB-452 fumarate) is a dopamine D2 receptor partial agonist. Aplindore fumarate could be used in studies of Parkinson's disease and schizophrenia .
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Cat. No.: HY-A0248AS
Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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Cat. No.: HY-107027
CAS No.: 1338055-88-1
Synonyms: Polymyxin E2 sulfate
Target:  

Bacterial Apoptosis

Research Areas:  

Infection

Colistin B (Polymyxin E2) sulfate is a major component of Colistin (HY-113678) and also an antibacterial agent active against multidrug-resistant Gram-negative bacteria. Colistin B sulfate exerts apoptotic effects on human renal proximal tubular cells. Colistin B sulfate induces mild to moderate renal histological damage in mouse models. Colistin B sulfate can be used in the research of multidrug-resistant Gram-negative bacterial infections .
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Cat. No.: HY-P11232
CAS No.: 1969250-99-4
Research Areas:  

Infection

NAB815 is a specific inhibitor of the Stx2a (Kd = 0.01 μM)/TLR4 interaction. NAB815 inhibits the neutrophil/Stx2a interaction (IC50 = 0.057 μg/mL). NAB815 inhibits the formation of Stx2-containing extracellular vesicles (EVs) produced by leukocytes and platelets and reduces their toxic effects in cellular (Vero cells) and animal models (CD-1 mice). NAB815 reduces bacterial loads in the kidneys, urine, and bladders of Escherichia coli-infected mice. NAB815 is useful in the study of hemolytic uremic syndrome (HUS) .
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Cat. No.: HY-107027S
Synonyms: Polymyxin E2-d7 TFA
Research Areas:  

Infection

Colistin B-d7 (Polymyxin E2-d7) TFA is the deuterated-labeled Colistin B (HY-184858). Colistin B is a major component of Colistin (HY-113678) and also an antibacterial agent active against multidrug-resistant Gram-negative bacteria. Colistin B exerts apoptotic effects on human renal proximal tubular cells. Colistin B induces mild to moderate renal histological damage in mouse models. Colistin B can be used in the research of multidrug-resistant Gram-negative bacterial infections .
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Cat. No.: HY-P11676
CAS No.: 1814918-91-6
Synonyms: BRII-693; QPX9003
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Soralimixin (BRII-693), a Polymyxin derivative, is a next-generation intravenous (IV)-administered synthetic macrocyclic peptide antibiotic. Soralimixin can be used for the study of infections caused by drug-resistant Gram-negative pathogens .
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Cat. No.: HY-A0248AS1
Polymyxin B1-D-Leu-d7 TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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