Colistin B-d7 TFA
Colistin B-d7 (Polymyxin E2-d7) TFA is the deuterated-labeled Colistin B (HY-184858). Colistin B is a major component of Colistin (HY-113678) and also an antibacterial agent active against multidrug-resistant Gram-negative bacteria. Colistin B exerts apoptotic effects on human renal proximal tubular cells. Colistin B induces mild to moderate renal histological damage in mouse models. Colistin B can be used in the research of multidrug-resistant Gram-negative bacterial infections.
For research use only. We do not sell to patients.
- Formula: C52H91D7N16O13·xC2HF3O2
- Molecular Weight:1162.48 (free base)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Molecular Weight 1162.48 (free base)
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Formula C52H91D7N16O13·xC2HF3O2
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Synonyms
Polymyxin E2-d7 TFA
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Sequence
{MOA}-{Dab}-Thr-{Dab}-{Dab}-{Dab}-{d-Leu}-{Leu-d7}-{Dab}-{Dab}-Thr (lactam: Dab4-Thr10)
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Sequence Shortening
{MOA}-{Dab}-Thr-{Dab}-{Dab}-{Dab}-{d-Leu}-{Leu-d7}-{Dab}-{Dab}-Thr (lactam: Dab4-Thr10)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Colistin B-d7 TFA Related Classifications
HY-107027S Related Classifications
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- Colistin B-d7
- Polymyxin E2-d7
- Isotope-Labeled Compounds
- Bacterial
- Apoptosis
- mouse models
- Pseudomonas aeruginosa
- multidrug-resistant Gram-negative bacteria
- Acinetobacter baumannii
- human kidney proximal tubular cells
- multidrug-resistant Gram-negative bacterial infections
- Klebsiella pneumoniae
- neutropenic mice
- Enterobacter cloacae
- HK-2 cells
- Inhibitor
- inhibitor
- inhibit