Soralimixin
Soralimixin (BRII-693), a Polymyxin derivative, is a next-generation intravenous (IV)-administered synthetic macrocyclic peptide antibiotic. Soralimixin can be used for the study of infections caused by drug-resistant Gram-negative pathogens.
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- No. CAS: 1814918-91-6
- Fòrmula: C48H80Cl2N16O13
- Peso molecular:1160.15
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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- Pureza y Documentación
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Actividad biológica
Descripciòn
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 1814918-91-6
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Peso molecular 1160.15
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Fòrmula C48H80Cl2N16O13
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Synonyms
BRII-693; QPX9003
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Sequence
{Dab(2,4-dichlorobenzaldehyde)}-{Thr}-{Dpr}-{Dab}-{Dab}-{d-Leu}-{Abu}-{Dab}-{Dab}-{Thr} (Lactam bridge: Dab4-Thr10)
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Sequence Shortening
{Dab(2,4-dichlorobenzaldehyde)}-{Thr}-{Dpr}-{Dab}-{Dab}-{d-Leu}-{Abu}-{Dab}-{Dab}-{Thr} (Lactam bridge: Dab4-Thr10)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Watkins M, et al. Phase 1 study of the safety, tolerability, and pharmacokinetics of a synthetic macrocyclic peptide antibiotic (BRII-693) in healthy adult participants. Antimicrob Agents Chemother. 2025 Jan 31;69(1):e0128824. [Content Brief]
[2]. Iovleva A, et al. Treatment Approaches for Carbapenem-Resistant Acinetobacter baumannii Infections. Drugs. 2025 Jan;85(1):21-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Soralimixin Related Classifications
HY-P11676 Related Classifications
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