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Cat. No.: HY-P11676

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Soralimixin

(Synonyms: BRII-693; QPX9003)

Soralimixin (BRII-693), a Polymyxin derivative, is a next-generation intravenous (IV)-administered synthetic macrocyclic peptide antibiotic. Soralimixin can be used for the study of infections caused by drug-resistant Gram-negative pathogens.

For research use only. We do not sell to patients.

CAS No.: 1814918-91-6
Formula: C₄₈H₈₀Cl₂N₁₆O₁₃
Molecular Weight:1160.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Soralimixin Chemical Structure

CAS No.: 1814918-91-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Antibiotic Isoforms :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 1814918-91-6
Molecular Weight 1160.15
Formula C₄₈H₈₀Cl₂N₁₆O₁₃
Synonyms

BRII-693; QPX9003
Sequence

{Dab(2,4-dichlorobenzaldehyde)}-{Thr}-{Dpr}-{Dab}-{Dab}-{d-Leu}-{Abu}-{Dab}-{Dab}-{Thr} (Lactam bridge: Dab4-Thr10)
Sequence Shortening

{Dab(2,4-dichlorobenzaldehyde)}-{Thr}-{Dpr}-{Dab}-{Dab}-{d-Leu}-{Abu}-{Dab}-{Dab}-{Thr} (Lactam bridge: Dab4-Thr10)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Watkins M, et al. Phase 1 study of the safety, tolerability, and pharmacokinetics of a synthetic macrocyclic peptide antibiotic (BRII-693) in healthy adult participants. Antimicrob Agents Chemother. 2025 Jan 31;69(1):e0128824. [Content Brief]

[2]. Iovleva A, et al. Treatment Approaches for Carbapenem-Resistant Acinetobacter baumannii Infections. Drugs. 2025 Jan;85(1):21-40. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References

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Soralimixin

All Antibiotic Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Soralimixin Related Classifications

HY-P11676 Related Classifications