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DG1

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By Targets:	Bacterial (1) Biochemical Assay Reagents (1) Drug Derivative (1) ERK (1) Interleukin Related (1) p38 MAPK (1) PKC (2) Ras (1) Small Interfering RNA (siRNA) (1) Thymidylate Synthase (1)
By Research Areas:	Cancer (4) Infection (1) Inflammation/Immunology (2) Metabolic Disease (2)
Oligonucleotides:	Nucleotide Analogs (1) Phospholipids (1) Human Pre-designed siRNA Sets (1) Cytidine Nucleotide (1) siRNAs (1)

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Biochemical Assay Reagents

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Products

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141572

1,2-Dioleoyl-sn-glycerol sn-1,2-Dioleoylglycerol; 18:1/18:1-DG	Drug Derivative	Metabolic Disease
1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol; 18:1/18:1-DG) is a glycerolipid located on the plasma membrane. 1,2-Dioleoyl-sn-glycerol consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. 1,2-Dioleoyl-sn-glycerol can induce acrosome reaction in human sperm ^[1] .

HY-143212

18:0-22:6 DG 1-Stearoyl-2-docosahexaenoyl-sn-glycerol	Ras p38 MAPK ERK PKC	Metabolic Disease Inflammation/Immunology Cancer
18:0-22:6 DG (1-Stearoyl-2-docosahexaenoyl-sn-glycerol) is a diacylglycerol (DG) that can interact with RasGRP (Ras guanine nucleotide-releasing protein) (K_i = 8.37 μM) and modulate the activation of MAP kinases (such as *ERK1/ERK2), which play a crucial role in cellular signaling processes. 18:0-22:6 DG can also activate protein kinase C* (PKC) isozyme. 18:0-22:6 DG can be used for research of cancer, immunology and metabolic disease ^[1] .

HY-N2040

(20R)-Protopanaxadiol 1 Publications Verification	Bacterial Interleukin Related	Infection Inflammation/Immunology Cancer
(20R)-Protopanaxadiol is a metabolite of ginsenosides. (20R)-Protopanaxadiol has anti-inflammatory and antibacterial activities, but shows no significant cytotoxicity against tumor cell lines. In addition, (20R)-Protopanaxadiol can inhibit the uptake of 2-deoxy-D-glucose (2-DG) .

HY-149352

*DG1*	Thymidylate Synthase	Cancer
DG1 (Compound 8Nc) is a Thymidylate Synthase (TS) inhibitor that affects cancer angiogenesis and metabolic reprogramming in NSCLC cells. DG1 can effectively inhibit the expression of CD26, ET-1, FGF-1 and EGF. DG1 also effectively inhibits the proliferation of cancer tissue in the A549 xenograft mouse model ^[1].

HY-RS04021

DSG1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DSG1 Human Pre-designed siRNA Set A contains three designed siRNAs for DSG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DSG1 Human Pre-designed siRNA Set A DSG1 Human Pre-designed siRNA Set A

HY-N15340

1-Oleoyl-2-linoleoyl-sn-glycerol	PKC	Cancer
1-Oleoyl-2-linoleoyl-sn-glycerol is a diacylglycerol (DG). 1-Oleoyl-2-linoleoyl-sn-glycerol can activate protein kinase C (PKC), thus triggering downstream signaling cascades and promoting tumor growth. 1-Oleoyl-2-linoleoyl-sn-glycerol is promising for research of breast cancer ^[1].

HY-164112

1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium 18:1 CDP DG	Biochemical Assay Reagents	Others
1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium (18:1 CDP DG) is a diacylglycerol derivate ^[1].

Cat. No.	Product Name	Type

HY-141572

1,2-Dioleoyl-sn-glycerol sn-1,2-Dioleoylglycerol; 18:1/18:1-DG	Biochemical Assay Reagents
1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol; 18:1/18:1-DG) is a glycerolipid located on the plasma membrane. 1,2-Dioleoyl-sn-glycerol consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. 1,2-Dioleoyl-sn-glycerol can induce acrosome reaction in human sperm ^[1] .

1,2-Dioleoyl-sn-glycerol

sn-1,2-Dioleoylglycerol; 18:1/18:1-DG

Biochemical Assay Reagents

1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol; 18:1/18:1-DG) is a glycerolipid located on the plasma membrane. 1,2-Dioleoyl-sn-glycerol consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. 1,2-Dioleoyl-sn-glycerol can induce acrosome reaction in human sperm ^[1] .

HY-143212

18:0-22:6 DG 1-Stearoyl-2-docosahexaenoyl-sn-glycerol	Biochemical Assay Reagents
18:0-22:6 DG (1-Stearoyl-2-docosahexaenoyl-sn-glycerol) is a diacylglycerol (DG) that can interact with RasGRP (Ras guanine nucleotide-releasing protein) (K_i = 8.37 μM) and modulate the activation of MAP kinases (such as *ERK1/ERK2), which play a crucial role in cellular signaling processes. 18:0-22:6 DG can also activate protein kinase C* (PKC) isozyme. 18:0-22:6 DG can be used for research of cancer, immunology and metabolic disease ^[1] .

18:0-22:6 DG

1-Stearoyl-2-docosahexaenoyl-sn-glycerol

Biochemical Assay Reagents

18:0-22:6 DG (1-Stearoyl-2-docosahexaenoyl-sn-glycerol) is a diacylglycerol (DG) that can interact with RasGRP (Ras guanine nucleotide-releasing protein) (K_i = 8.37 μM) and modulate the activation of MAP kinases (such as ERK1/ERK2), which play a crucial role in cellular signaling processes. 18:0-22:6 DG can also activate protein kinase C (PKC) isozyme. 18:0-22:6 DG can be used for research of cancer, immunology and metabolic disease ^[1] .

HY-164112

1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium 18:1 CDP DG	Biochemical Assay Reagents
1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium (18:1 CDP DG) is a diacylglycerol derivate ^[1].

(20R)-Protopanaxadiol 1 Publications Verification	Panax ginseng C. A. Meyer Infection Triterpenes Classification of Application Fields Terpenoids Plants Disease Research Fields Araliaceae Source Classification	Bacterial Interleukin Related
(20R)-Protopanaxadiol is a metabolite of ginsenosides. (20R)-Protopanaxadiol has anti-inflammatory and antibacterial activities, but shows no significant cytotoxicity against tumor cell lines. In addition, (20R)-Protopanaxadiol can inhibit the uptake of 2-deoxy-D-glucose (2-DG) .

1-Oleoyl-2-linoleoyl-sn-glycerol	Natural Products Endogenous metabolite Source Classification	PKC
1-Oleoyl-2-linoleoyl-sn-glycerol is a diacylglycerol (DG). 1-Oleoyl-2-linoleoyl-sn-glycerol can activate protein kinase C (PKC), thus triggering downstream signaling cascades and promoting tumor growth. 1-Oleoyl-2-linoleoyl-sn-glycerol is promising for research of breast cancer ^[1].

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83128

	Desmoglein 1 Antibody (YA2873) Desmoglein-1; Desmosomal glycoprotein 1; DG1; DGI; Pemphigus foliaceus antigen; Cadherin family member 4; DSG1; CDHF4	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Desmoglein 1 Antibody (YA2873) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Desmoglein 1.

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Cat. No.	Product Name		Classification

HY-143212

18:0-22:6 DG 1-Stearoyl-2-docosahexaenoyl-sn-glycerol		Phospholipids
18:0-22:6 DG (1-Stearoyl-2-docosahexaenoyl-sn-glycerol) is a diacylglycerol (DG) that can interact with RasGRP (Ras guanine nucleotide-releasing protein) (K_i = 8.37 μM) and modulate the activation of MAP kinases (such as *ERK1/ERK2), which play a crucial role in cellular signaling processes. 18:0-22:6 DG can also activate protein kinase C* (PKC) isozyme. 18:0-22:6 DG can be used for research of cancer, immunology and metabolic disease ^[1] .

HY-RS04021

DSG1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
DSG1 Human Pre-designed siRNA Set A contains three designed siRNAs for DSG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-164112

1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium 18:1 CDP DG		Nucleotide Analogs Cytidine Nucleotide
1,2-Dioleoyl-sn-glycero-3-(cytidine diphosphate) ammonium (18:1 CDP DG) is a diacylglycerol derivate ^[1].

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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DG1

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Antibodies

Oligonucleotides

Natural
Products