24529-88-2
Chemical Structure
1,2-Dioleoyl-sn-glycerol
Synonym(s): sn-1,2-Dioleoylglycerol; 18:1/18:1-DG
- CAS No.: 24529-88-2
- Formula:C39H72O5
- Molecular Weight:620.99
IUPAC Name: (S)-3-hydroxypropane-1,2-diyl dioleate
InChIKey: AFSHUZFNMVJNKX-LLWMBOQKSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(O[C@@H](CO)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O
Biological Activity: 1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol; 18:1/18:1-DG) is a glycerolipid located on the plasma membrane. 1,2-Dioleoyl-sn-glycerol consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. 1,2-Dioleoyl-sn-glycerol can induce acrosome reaction in human sperm [1][2].
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1,2-Dioleoyl-sn-glycerol | 99.96% | 1,2-Dioleoyl-sn-glycerol (sn-1,2-Dioleoylglycerol; 18:1/18:1-DG) is a glycerolipid located on the plasma membrane. 1,2-Dioleoyl-sn-glycerol consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. 1,2-Dioleoyl-sn-glycerol can induce acrosome reaction in human sperm . | ||||||||||||||||||||
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References
- [1]. Komenoi S, et al. Diacylglycerol kinase η1 is a high affinity isozyme for diacylglycerol. FEBS Lett. 2015 May 8;589(11):1272-7. [Content Brief]
- [2]. Doherty CM, et al. Characterization of two second messenger pathways and their interactions in eliciting the human sperm acrosome reaction. J Androl. 1995 Jan-Feb;16(1):36-46. [Content Brief]
